Histoplasmosis

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Histoplasmosis trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 3

NCT05814432

Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS

Phase III trial evaluating the safety and efficacy of a single high dose (10 mg/kg) of liposomal amphotericin B for disseminated histoplasmosis in AIDS patients…

Brazil279 participantsStarted 2025-01-16

Treatment: Single high dose of liposomal amphotericin B, L-AmB standard dose

All recent trials (30 shown)

Not Yet RecruitingPhase 3

NCT07261150

Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)

The purpose of the study is threefold: 1. Assess the safety and efficacy of a single high-dose intravenous (LAmB 10mg/kg) compared to the SOC daily dosing (3mg…

United States, Brazil664 participantsStarted 2026-09-15

Treatment: LAmB B, Posaconazole

CompletedPhase 2

NCT04059770

Randomized Trial of Liposomal Amphotericin B for Histoplasmosis in AIDS Patients

Disseminated histoplasmosis (DH) is one of the major AIDS-defining infections responsible for high mortality rates in HIV-infected patients. Liposomal amphoteri…

Brazil118 participantsStarted 2020-02-14

Treatment: single dose of L-AmB, 2 doses of L-AmB

Histoplasmosis

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS

All recent trials (30 shown)

Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)

Randomized Trial of Liposomal Amphotericin B for Histoplasmosis in AIDS Patients

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS

All recent trials (30 shown)

Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)

Randomized Trial of Liposomal Amphotericin B for Histoplasmosis in AIDS Patients

Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or In…

Prevalence of Histoplasmosis in HIV + Patients with a Rapid Diagnostic Test in West Indies

Endemic Mycoses Treatment With SUBA-itraconazole vs Itraconazole

Point of Care Tests to Identify Opportunistic Infections in Advanced HIV Patients in Mexico City

A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDS

Pilot Study to Determine the Feasibility of Fluconazole for Induction Treatment and Suppression of Relapse of Histoplasm…

A Study of Itraconazole in Preventing the Return of Histoplasmosis, a Fungal Infection, in Patients With AIDS

Intravitreal Aflibercept Injection (IAI) for Presumed Ocular Histoplasmosis Syndrome

Additive Benefit of the Urine LAM Test to Current TB Diagnostics in HIV Positive Adults in Panama City, Panama

A Clinical Study to Evaluate the Pharmacokinetics of Lozanoc and Sporanox in Korean Healthy Male Volunteers

Treatment for Presumed Ocular Histoplasmosis

Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD

A Multi-center Study of Spherule-Derived Coccidioidin

A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those Wit…

Submacular Surgery Trials (SST)

Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization in Ocular Histoplasmosis Syndrome

Ranibizumab Versus PDT for Presumed Ocular Histoplasmosis

A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) Infection