Cholera Vaccination

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Cholera Vaccination trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

RecruitingPhase 2

NCT07509047

Age-descending Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Adults and Children

This phase II study is intended to determine the immunogenicity and safety of single dose and two doses of OSP:rTTHc cholera conjugate vaccine (CCV) with or wit…

Kenya390 participantsStarted 2026-01-13

Treatment: OSP:rTTHc CCV 25 ㎍ with Aluminum phosphate, OSP:rTTHc CCV 25 ㎍ without Aluminum phosphate

RecruitingPhase 4

NCT07487077

Extended Dosing Intervals Trial for Oral Cholera Vaccine, Kenya

Background: Despite efforts to control cholera, outbreaks continue to occur in Kenya. Oral cholera vaccines (OCVs) are a critical tool in cholera prevention str…

Kenya1,071 participantsStarted 2025-10-31

Treatment: Euvichol-S Oral Cholera Vaccine

RecruitingPhase 3

NCT07304284

Trial to Evaluate Immunogenicity Non-Inferiority, Safety and Lot-to-Lot Consistency of Biovac OCV-S to Euvichol®-Plus

This Phase I/III clinical trial is intended to establish the immunogenicity and safety profile of Biovac OCV-S compared to available WHO pre-qualified vaccine E…

South Africa2,824 participantsStarted 2025-10-31

Treatment: Experimental: Biovac OCV-S (inactivated whole-cell monovalent (O1) oral cholera vaccine), Active Comparator, Euvichol®-Plus

RecruitingPhase 4

NCT03705585

CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera

This is an open-label, non-randomized study. The purpose of this study is to better understand how vaccines against typhoid fever and cholera affect the normal…

United States240 participantsStarted 2018-11-05

Treatment: Vivotif Typhoid Oral Vaccine, Vaxchora

RecruitingNot Applicable

NCT04853186

Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance

This project aims to fill this essential knowledge gap by assessing the impact of oral cholera vaccine mass campaigns in 2 sites (urban and rural) in DRC, descr…

Democratic Republic of the Congo6,000 participantsStarted 2021-05-11

All recent trials (27 shown)

Not Yet RecruitingPhase 1

NCT07270796

Safety and Immunogenicity Study of the DuoChol Oral Cholera Vaccine in Healthy Participants

The goal of this phase I, open-label, randomized, active-controlled Trial is to evaluate the safety and immunogenicity of the DuoChol Oral Cholera Vaccine in 18…

Sweden60 participantsStarted 2027-01

Treatment: DuoChol, Dukoral®

CompletedPhase 2

NCT03251495

Immunologic Responses to a Live Attenuated Oral Cholera Vaccine

The primary objective of this study is to evaluate the antibody response to the cholera vaccine, Vaxchora®, in healthy subjects. Investigators also seek to eva…

United States34 participantsStarted 2017-08-29

Treatment: Vaxchora

Cholera Vaccination

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Age-descending Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Adults and Children

Extended Dosing Intervals Trial for Oral Cholera Vaccine, Kenya

Trial to Evaluate Immunogenicity Non-Inferiority, Safety and Lot-to-Lot Consistency of Biovac OCV-S to Euvichol®-Plus

CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera

Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance

All recent trials (27 shown)

Safety and Immunogenicity Study of the DuoChol Oral Cholera Vaccine in Healthy Participants

Immunologic Responses to a Live Attenuated Oral Cholera Vaccine

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Age-descending Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Adults and Children

Extended Dosing Intervals Trial for Oral Cholera Vaccine, Kenya

Trial to Evaluate Immunogenicity Non-Inferiority, Safety and Lot-to-Lot Consistency of Biovac OCV-S to Euvichol®-Plus

CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera

Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance

All recent trials (27 shown)

Safety and Immunogenicity Study of the DuoChol Oral Cholera Vaccine in Healthy Participants

Immunologic Responses to a Live Attenuated Oral Cholera Vaccine

Phase 1b Ascending Dose Study of PanChol in Healthy Volunteers

Dose Escalation Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Healthy Adults

Immune Response Elicited by Concomitant Administration of Oral Typhoid Fever (Vivotif®) and Cholera (Dukoral®) Vaccines

Impact Study of Cholera Vaccination in Endemic Areas - Seroprevalence

Follow-up of Pregnant Women After a Mass Vaccination of Oral Cholera Vaccine (ShancholTM) in Nsanje Malawi

Safety and Efficacy Challenge Study of Live Oral Cholera Vaccine Candidate,PXVX0200, to Prevent Cholera

Blood Donor CVD 9000

Extended Dose Intervals With Oral Cholera Vaccine in Cameroon

Cholera Vaccine Investment Strategy in Bangladesh

Effect of Milk on the Vaccination Response

Effect of Raw Milk on the Immune Response Upon Cholera Vaccination

Introduction of Cholera Vaccine in Bangladesh

Oral Cholera Vaccine Delivery in Rural Bangladesh

Transcutaneous Immunization With an Attenuated Listeria Monocytogenes Vector Vaccine

Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infants

Mucosal Response in Immunocompromised Host

Study of Alternative Vaccination Schedule of Oral Cholera Vaccine

Effectiveness of a Bivalent Killed Whole Cell Based Oral Cholera Vaccine