Stopped: lack of funding
This is an open-label, non-randomized study. Volunteers will be vaccinated with the oral cholera vaccine, Vaxchora. Vaxchora has been licensed by the Food and Drug Administration (FDA) for travelers to developing countries. Volunteers will also be asked to provide blood specimens over a follow-up time period of up to eight years. The specimens obtained in this clinical research study will be used to further the investigator's understanding of the protective immunological mechanisms that can be elicited systemically and may be applicable to other enteric pathogens.
Age range
18 Years – 64 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in the Absolute Percentage of Positive CD4+ CD25+/OX40+ T Cells
Timeframe: Baseline and Day 3
Change in Absolute Percentage of Positive CD4+ CD25+/OX40+ T Cells
Timeframe: Baseline and Day 5
Change in Absolute Percentage of Positive CD4+ CD25+/OX40+ T Cells
Timeframe: Baseline and Day 8
Change in Absolute Percentage of Positive CD4+ CD25+/OX40+ T Cells
Timeframe: Baseline and Day 10
Change in Absolute Percentage of Positive CD4+ CD25+/OX40+ T Cells
Timeframe: Baseline and Day 15
Change in Absolute Percentage of Positive CD4+ CD25+/OX40+ T Cells
Timeframe: Baseline and Day 29
Change in Absolute Percentage of Positive T Follicular/Helper 17 Cells Expressing CD154
Timeframe: Baseline and Day 1
Change in Absolute Percentage of Positive T Follicular/Helper 17 Cells Expressing CD154
Timeframe: Baseline and Day 3
Change in Absolute Percentage of Positive T Follicular/Helper 17 Cells Expressing CD154
Timeframe: Baseline and Day 5
Change in Absolute Percentage of Positive T Follicular/Helper 17 Cells Expressing CD154
Timeframe: Baseline and Day 8
Change in Absolute Percentage of Positive T Follicular/Helper 17 Cells Expressing CD154
Timeframe: Baseline and Day 10
Change in Absolute Percentage of Positive T Follicular/Helper 17 Cells Expressing CD154
Timeframe: Baseline and Day 15
Change in Absolute Percentage of Positive T Follicular/Helper 17 Cells Expressing CD154
Timeframe: Baseline and Day 29