Immunologic Responses to a Live Attenuated Oral Cholera Vaccine

Inclusion Criteria: * Capable of informed consent and provision of written informed consent before any study procedures * Capable of attending all study visits according to the study schedule * Are in good health, as determined by medical history and targeted physical exam related to this history * Female subjects of childbearing age must have a negative urine pregnancy test before study vaccination, and must use two forms of contraception to avoid pregnancy within one month of Vaxchora administration Exclusion Criteria: * Have an acute illness within 72 hours before vaccination * Have any acute or chronic medical condition that, in the opinion of the principal investigator, would make vaccination unsafe or interfere with the evaluation of immune response to study vaccination * Have a suppressed immune system as a result of illness, immunosuppressive medication, chemotherapy, or radiation therapy within 3 years prior to study vaccination * Have taken oral or parenteral corticosteroids of any dose within 30 days before study vaccination * Reside with individuals under the age of 2 or with an immunocompromised individuals * Have a known history of autoimmune disease * Have a history of Guillain-Barre Syndrome * Have plans to receive any vaccine from 28 days prior to study vaccination until Day 29 * Has previously received a cholera vaccine or have a known history of V. Cholerae. * Have donated blood or blood products within 56 days before study vaccination, plan to donate bl…