Chagas Heart Disease

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Chagas Heart Disease trials may be worth asking about

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingNot Applicable

NCT05519046

Cardiac Contractility Modulation in Chagas Heart Disease

Chagas disease is an endemic problem in Latin America, where millions of people are chronically infected with T. cruzi. Recently, it was assumed to have clinica…

Brazil60 participantsStarted 2022-05-25Updated 2025-04-04

Treatment: Cardiac Contractility Modulation (CCM), CRT

All recent trials (34 shown)

CompletedPhase 4

NCT04023227

Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Pat…

The purpose of this study was to evaluate the effect of sacubitril/valsartan 200 mg BID compared with enalapril 10 mg BID, in addition to conventional heart fai…

Argentina, Brazil +2 more922 participantsStarted 2019-12-10Updated 2026-05-11

Treatment: Sacubitril/valsartan, Enalapril

CompletedNot Applicable

NCT04239144

Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease

Ventricular tachycardia (VT) is the main cause of sudden death in patients with structural heart diseases. The use of ICD (implantable cardio-defibrillator) cou…

Brazil45 participantsStarted 2018-11-09

Chagas Heart Disease

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Cardiac Contractility Modulation in Chagas Heart Disease

All recent trials (34 shown)

Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Pat…

Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Cardiac Contractility Modulation in Chagas Heart Disease

All recent trials (34 shown)

Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Pat…

Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease

Short Benznidazole Regimen for Chronic Phase Chagas Disease Patients

Cardiac Mechanics by Speckle Tracking as a Prognostic Predictor in Patients With Chagas Cardiomyopathy

Atorvastatin on Inflammation and Cardiac Function in Chronic Chagas Disease

SBRT in Chagas Disease Ventricular Tachycardia

Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF.

Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)

Amiodarone Against ICD Therapy in Chagas Cardiomyopathy for Primary Prevention of Death

Microvascular Endothelial Function in a Cohort of Patients With the Cardiac Form of Chronic Chagas Disease.

Congenital Chagas Disease: Long Term Follow up of Treated Children. Preliminary Report or Cardiological Evaluation in Ch…

BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease

Colchicine for Patients With Chagas´ Disease( B1 Stage)

Physical Exercise Program in Chronic Chagas Heart Disease

A Trial Testing Amiodarone in Chagas Cardiomiopathy

Cell Therapy in Chagas Cardiomyopathy

Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas Disease

Effects of Omega-3 Supplementation on the Cytokine and Lipid Profiles in Patients With Chronic Chagas Cardiomyopathy

Chagas Disease as an Undiagnosed Type of Cardiomyopathy in the United States

Genetic Architecture of Heart Disease in Rural Brazil