CompletedPhase 3

Physical Exercise Program in Chronic Chagas Heart Disease

Brazil30 participantsStarted 2015-03

Plain-language summary

The aim of this investigation is to evaluate the impact of exercise in a cardiac rehabilitation program on functional capacity, clinical markers, quality of life and biomarkers in patients with chronic chagasic cardiomyopathy.

Who can participate

Age range18 Years

SexALL

See this in plain English?

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Inclusion Criteria: (1) Chagas disease diagnosis by serology; (2) chronic chagasic cardiomyopathy, with left ventricular ejection fraction \<45% or compensated heart failure (3) clinical stability in the last three months, (4) adherence to the ambulatory clinical treatment and (5) age above 18 years. Exclusion Criteria: (1) pregnancy, (2) neuromuscular limitations, (3) tobacco use, (4) evidence of nonchagasic heart disease, (5) systemic conditions that limits exercise practice or hemodynamic stress tests (6) unavailability to attend three times a week for a minimum of six months, (7) practitioners of regular exercise and (8) claustrophobia.

What they're measuring

Functional capacity measured by peak exercise oxygen consumption

Timeframe: Changes from baselint at three and six months

Trial details

NCT IDNCT02517632

SponsorEvandro Chagas National Institute of Infectious Disease

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-01

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