Cell Therapy in Chagas Cardiomyopathy

Inclusion Criteria: * Diagnosis of dilated cardiomyopathy according to WHO criteria * Syndromic heart failure in functional class III or IV of the NYHA * Enrollment and continuous follow-up in cardiac out-patient clinic * Adequate medical therapy after optimization therapy * Echocardiogram with an ejection fraction equal to or less than 35% by Simpson's rule Exclusion Criteria: * Valvular diseases, except functional mitral or tricuspid reflow * Coronariography showing a significant lesion (obstruction of at least 50% of the lumen in the troncus or the main arteries - LAD, CX, RC) in one or more arteries * Serologic diagnosis for Chagas disease or at least two of the following criteria: epidemiology, right bundle branch block, anterior hemi-block, apical aneurism * Sustained ventricular tachycardia * Abusive use of alcohol or illicit drugs * Pregnancy * Use of cardio toxic drugs * Any co-morbidity with impact in life expectancy in 2 years * Renal function compromised (creatinine above 2 mg/dl) * Definitive implant of pace-makers, resynchronizers and CDIs * Heart failure with symptoms initiating less than 1 year ago * Active systemic arterial hypertension or history of hypertension