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BRCA1 Gene Mutation
Clinical trial pipeline · Data from ClinicalTrials.gov
See which BRCA1 Gene Mutation trials may be worth asking aboutClinical trial pipeline · Data from ClinicalTrials.gov
See which BRCA1 Gene Mutation trials may be worth asking aboutNorth America
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Background: A germline mutation is a change to a person s genes that is carried through their DNA. These mutations can be passed on from parents to their offsp…
This phase II trial investigates how well the addition of olaparib following completion of surgery and chemotherapy works in treating patients with pancreatic c…
The purpose of this phase 1 clinical trials is to determine whether niraparib (a Poly (ADP-ribose) polymerase inhibitor (PARPi)) can be safely combined with iri…
This is an open-label, multi-center, phase 1b study designed to determine a tolerable dose of CX-5461 administered by IV infusion on Day 1 and Day 8 of a 28-day…
This is a single center, phase I/Ib clinical trial evaluating the combination of the poly adenosine diphosphate-ribose polymerase (PARP) inhibitor olaparib with…
The aim of the COVAR project is to achieve reliable classification of as many variants of interest as possible from the French OncoGenetics Database (FrOG, http…
This phase Ib trial studies the best dose and side effects of niraparib and copanlisib in treating patients with endometrial, ovarian, primary peritoneal, or fa…
This study will compare two different regimens for patients with BRCA1/2 or PALB2 mutated metastatic pancreatic cancer after progression on first-line FOLFIRINO…