Anoxic Brain Injury

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Anoxic Brain Injury trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

RecruitingPhase 2

NCT05778188

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Mo…

Hypoxic-ischemic encephalopathy (HIE) affects approximately 4,000 to 12,000 persons annually in the United States. Mortality from HIE has been reported up to 60…

United States70 participantsStarted 2023-07-27

Treatment: RLS-0071, Placebo

RecruitingNot Applicable

NCT07413900

Biomarkers Study in Infants With Prior Neonatal Brain Injury

This research focuses on the long-term cognitive development of children, including healthy infants and those who had a perinatal brain injury. As part of this…

United States100 participantsStarted 2023-03-13

RecruitingNot Applicable

NCT06979700

Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest

WAKE-OHCA is a prospective observational substudy of the Danish Out-of-Hospital Cardiac Arrest (DANOHCA) trial, identifier NCT05895838. The aim is to collect ea…

Denmark250 participantsStarted 2025-05-13

Treatment: Automated Pupillometry, Transcranial Doppler Ultrasound

RecruitingNot Applicable

NCT04080440

Brain-injured Patients Extubation Readiness Study

The BIPER study is a stepped wedge cluster randomised clinical trial aiming to decrease extubation failure in critically-ill brain-injured patients with residua…

France660 participantsStarted 2020-02-09

Treatment: Extubation readiness clinical score, Usual Care

RecruitingPhase 2

NCT05004610

Hypertonic Lactate After Cardiac Arrest

The study is intended to test the hypothesis that sodium lactate infusion after resuscitation from a cardiac arrest will decrease the magnitude of brain damage,…

Belgium125 participantsStarted 2025-02-19

Treatment: Sodium Lactate Solution

All recent trials (30 shown)

Active — Not RecruitingNot Applicable

NCT03243539

Implementation of Neuro Lung Protective Ventilation

Patients who experience lung injury are often placed on a ventilator to help them heal; however, if the ventilator volume settings are too high, it can cause ad…

United States728 participantsStarted 2017-08-31

Treatment: Lung Protective Ventilation

By InvitationNot Applicable

NCT07264166

Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)

This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with…

Mexico25 participantsStarted 2026-03-01

Anoxic Brain Injury

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Mo…

Biomarkers Study in Infants With Prior Neonatal Brain Injury

Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest

Brain-injured Patients Extubation Readiness Study

Hypertonic Lactate After Cardiac Arrest

All recent trials (30 shown)

Implementation of Neuro Lung Protective Ventilation

Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Mo…

Biomarkers Study in Infants With Prior Neonatal Brain Injury

Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest

Brain-injured Patients Extubation Readiness Study

Hypertonic Lactate After Cardiac Arrest

All recent trials (30 shown)

Implementation of Neuro Lung Protective Ventilation

Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)

Florida Cerebrovascular Disease Biorepository and Genomics Center

High Dose of Erythropoietin Analogue After Cardiac Arrest

Stimulant Therapy Targeted to Individualized Connectivity Maps to Promote ReACTivation of Consciousness

Dexmedetomidine Versus Morphine During Cooling Therapy in Neonates

Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination

Brain Network Disruptions Related to Traumatic Coma

Excitatory Prefrontal Weak Current Stimulation in Vegetative Patients

Early DiaGnosis of Anoxic Brain Injury for Resuscitated Patients

CONNECT-ME: Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG

Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor

TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation

Diet Induced Ketosis for Brain Injury - A Feasibility Study

Evaluation of the "Pupillary Pain Index" in Neurological Prognosis After Cardiac Arrest

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerab…

Sub-study of the NEURODOC Project : Neurophysiological Evaluation of a Routine Care Open Label tDCS Session

Antioxidant and NMDA Receptor Blocker Wins Anoxic Brain Damage of KorEa OHCA Patients

Study for the Improvement of Long-Term Outcome Prediction in Patients in Coma After Cardiac Arrest

Temperature Control With an Esophageal Cooling Device in Post Cardiac Arrest Patients