CompletedNot Applicable

Diet Induced Ketosis for Brain Injury - A Feasibility Study

Denmark12 participantsStarted 2020-10-05

Plain-language summary

Each year, approx. 100 patients with severe brain injury is admitted to the Clinic for Neurorehabilitation/TBI Unit, Rigshospitalet. Severe brain injury results in local oxygen deficiency and acid formation in the brain, which together destroys brain cells. The purpose of this study is to investigate whether it is possible to carry out a ketogenic diet therapy for patients with severe brain injury for six weeks. Ketosis has been shown to be neuroprotective during and after severe brain injury.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed with severe acquired brain injury (TBI, stroke, SAH, anoxic brain injury or neuroinfection) * Patients ≥ 18 years * Understand and speak Scandinavian language * Informed consent from patient or deputy consent if the patient is unable to give consent due to reduced state of consciousness * Expectation of prolonged hospitalization Exclusion Criteria: * Contraindication to a ketogenic diet * Dysregulated Diabetes Mellitus * Medicated for elevated triglycerides

What they're measuring

Can the intervention be completed during 6 weeks hospitalization

Timeframe: 6 weeks

The occurrence of adverse reactions related to the ketogenic treatment, specified

Timeframe: 6 weeks

Can patients accept the treatment

Timeframe: 6 weeks

Trial details

NCT IDNCT04308577

SponsorJens Rikardt Andersen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-02-09

View on ClinicalTrials.gov More Brain Injuries trials