Adenocarcinoma Gastric Stage IV With Metastases

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Adenocarcinoma Gastric Stage IV With Metastases trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingPhase 2

NCT07556640

LM-302 and S-1 Plus Intraperitoneal Paclitaxel With or Without Cadonilimab for Claudin 18.2-positive Gastric or Gastroes…

In this study, the investigators will use LM-302 and S-1 plus intraperitoneal paclitaxel with or without Cadonilimab to treat Claudin 18.2-positive gastric or g…

China74 participantsStarted 2026-04-17

Treatment: LM-302, S-1, paclitaxel, LM-302, Cadonilimab, S-1, paclitaxel

RecruitingPhase 1

NCT06364410

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients Wi…

This phase I trial tests the safety, side effects, and best dose of azenosertib in combination with trastuzumab deruxtecan in treating patients with HER2-positi…

United States48 participantsStarted 2025-02-03

Treatment: Azenosertib, Biopsy Procedure

RecruitingPhase 1/2

NCT05269381

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

This phase I/II trial tests the safety and tolerability of an experimental personalized vaccine when given by itself and with pembrolizumab in treating patients…

United States132 participantsStarted 2022-03-31

Treatment: Cyclophosphamide, Neoantigen Peptide Vaccine

RecruitingPhase 1

NCT05802056

Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis

This phase Ib trial test effects of aldesleukin in combination with nivolumab and standard chemotherapy in treating patients with gastric cancer that has spread…

United States15 participantsStarted 2023-11-29

Treatment: Aldesleukin, Biopsy

All recent trials (38 shown)

Active — Not RecruitingPhase 1

NCT04460937

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal an…

This phase I trial investigates the side effects and best dose of adavosertib and how well it works when given in combination with radiation therapy in treating…

United States4 participantsStarted 2021-04-09

Treatment: Adavosertib, Radiation Therapy

Active — Not RecruitingPhase 1

NCT04704661

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expre…

The dose escalation phase of this trial identifies the safety, side effects and best dose of ceralasertib (AZD6738) when given in combination with trastuzumab d…

United States51 participantsStarted 2021-08-09

Treatment: Biopsy Procedure, Biospecimen Collection

Adenocarcinoma Gastric Stage IV With Metastases

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

LM-302 and S-1 Plus Intraperitoneal Paclitaxel With or Without Cadonilimab for Claudin 18.2-positive Gastric or Gastroes…

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients Wi…

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis

All recent trials (38 shown)

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal an…

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expre…

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

LM-302 and S-1 Plus Intraperitoneal Paclitaxel With or Without Cadonilimab for Claudin 18.2-positive Gastric or Gastroes…

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients Wi…

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis

All recent trials (38 shown)

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal an…

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expre…

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)

Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophag…

Capecitabine, Epirubicin, and Carboplatin in Treating Patients With Progressive, Unresectable, or Metastatic Cancer

Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors

Intraperitoneal Chemotherapy in Gastric Cancer With Peritoneal Carcinomatosis

A Study of Apatinib Tablets in the Treatment of Advanced or Metastatic Gastric Cancer

Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malig…

E-MOSAIC Electronic Tool to Monitor Symptoms

Irinotecan and Capecitabine in Treating Patients With Solid Tumors

TKM 080301 for Primary or Secondary Liver Cancer

Hyperthermic Intraperitoneal Chemotherapy for Advanced Gastric Cancer With Peritoneal Metastatis

Massage Therapy in Treating the Symptoms of Patients With Locally Advanced or Metastatic Cancer

Bortezomib, Paclitaxel, and Carboplatin in Treating Patients With Unresectable, Metastatic Cancer of the Esophagus or Ga…

Docetaxel and Capecitabine in Treating Patients With Metastatic Cancer of the Stomach or Gastroesophageal Junction

Irradiated Donor Lymphocyte Infusion in Treating Patients With Relapsed or Refractory Hematologic Cancer or Solid Tumor

Vaccine Therapy in Treating Patients With Advanced or Metastatic Cancer

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain