Acute Mountain Sickness (AMS)

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Acute Mountain Sickness (AMS) trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 4

NCT07118462

HighCycle Study: Acetazolamide, High Altitude and Plasma Volume

Each year, millions of people living at low altitude (\< 1,000 m) travel to high altitude (≥ 2,500 m) for work, tourism, or sports activities. These individuals…

Kyrgyzstan270 participantsStarted 2024-07-15

Treatment: Acetazolamide, Placebo

All recent trials (13 shown)

Active — Not RecruitingEarly Phase 1

NCT07517068

The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude

High altitude travel can lead to inflammation in the body and activation of innate immune cells. The investigators' prior research demonstrates that 1 to 3 days…

United States19 participantsStarted 2025-09-17

Treatment: ACETAZOLAMIDE oral capsule, Placebo Arm

Not Yet RecruitingNot Applicable

NCT07148674

Efficacy of Positive Expiratory Pressure on Acute Mountain Sickness

This pilot study aims to evaluate the efficacy of positive expiratory pressure (PEP) therapy at 10 cmH₂O in improving peripheral oxygen saturation (SpO₂) and mi…

Location not specified3 participantsStarted 2025-09-05

Treatment: Positive Expiratory Pressure (10cmH2O) in hypobaric hypoxia

Acute Mountain Sickness (AMS)

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

HighCycle Study: Acetazolamide, High Altitude and Plasma Volume

All recent trials (13 shown)

The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude

Efficacy of Positive Expiratory Pressure on Acute Mountain Sickness

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

HighCycle Study: Acetazolamide, High Altitude and Plasma Volume

All recent trials (13 shown)

The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude

Efficacy of Positive Expiratory Pressure on Acute Mountain Sickness

Safety and Efficacy of T89 in the Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)

Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness

Optimization Strategy for the Prevention of AMS by RIPC Combined With Acetazolamide

Comparison of Metoclopramide and Ibuprofen for the Treatment of Acute Mountain Sickness

Safety and Efficacy of T89 in Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)

Ibuprofen vs Acetaminophen for AMS Prevention

Evaluation of the Prevention and Treatment Effects of Chinese Medicine on High Altitude Illness

Can Rhodiola Crenulata Intake Improve Oxygen Saturation and Decrease the Incidence of Acute Mountain Sickness

Change in Peripheral Oxygen Saturation by Using Different Breathing Procedures in High Altitude

Training in Hypoxia to Prevent Acute Mountain Sickness