Optimization Strategy for the Prevention of AMS by RIPC Combined With Acetazolamide

Inclusion Criteria: * People who live in plain areas all year round and have not been to an altitude of 1500 meters or more in the past 30 days; * Sign the informed consent form voluntarily. Exclusion Criteria: * Chronic physical or mental diseases, including hypertension, diabetes, coronary heart disease, cerebrovascular disease, chronic obstructive pulmonary disease, migraine, anxiety, depression, insomnia, etc.; * The female is pregnant or in the period of preparing for pregnancy or breast-feeding; * Have a history of smoking; * Have a history of thrombosis in the upper limbs; * Severe damage to local soft tissues of upper limbs, fractures, etc.; * Allergic to sulfa; * Are taking one or more drugs; * Past laboratory tests suggest hypokalemia, hyponatremia, or liver and kidney damage; * Patients unsuitable for enrollment in the clinical trial according to investigators decision making.