CompletedNot Applicable

Impact of Procalcitonin on the Management of Children Aged 1 to 36 Month Presenting With a Fever Without a Source

Canada384 participantsStarted 2006-11

Plain-language summary

Serious bacterial infections are often difficult to detect in children with fever without source. Procalcitonin is a better blood marker of infection than White blood cell count and possibly than C-reactive protein. This could lead to a reduction in antibiotic prescription. Our objective is to evaluate the impact of Procalcitonin result on antibiotic prescription in children 1 to 36 month old with fever without source and our hypothesis is that it will lower the antibiotic prescription rate

Who can participate

Age range1 Month – 36 Months

SexALL

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Inclusion Criteria: * Children 1-36 months * With rectal temperature \>38.0 C * And no identified source of infection after history and physical examination Exclusion Criteria: * acquired or congenital immunodeficiency

What they're measuring

Difference in prescription of antibiotics between the two groups, excluding those treated for a bacterial infection identified by the ED investigations

Trial details

NCT IDNCT00692848

SponsorSt. Justine's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2007-11

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