Procalcitonin

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Procalcitonin trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 9 trials

RecruitingNot Applicable

NCT03244293

Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis

To evaluate the discriminative power of BIS monitoring to classify the degree of mental state associated with the PCT graded sepsis cascade, and to assess its u…

China20 participantsStarted 2014-01-01

Treatment: no intervention

RecruitingNot Applicable

NCT07350785

Prediction of Mortality and Morbidity After Hip Fracture Using Monocyte Distribution Width (MDW)

Hip fracture is a common injury in older adults and is often associated with serious complications, longer hospital stays, and increased risk of death. One of t…

Greece100 participantsStarted 2024-12-01

RecruitingNot Applicable

NCT07211620

KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use - Comparing Procalcitonin Kinetics-guided and Absolute Pr…

The study aims to compare the efficacy and safety of an absolute procalcitonin (PCT) value-guided antibiotic initiation protocol and a protocol using the kineti…

Hungary250 participantsStarted 2025-11-06

Treatment: Kinetics, Absolute

RecruitingNot Applicable

NCT07200817

Neutrophils to Lymphocytes and Platelets Ratio, Procalcitonin, and Total Leucocytic Count as Indicators of Prognostic Ou…

This study aims to compare Neutrophil to Lymphocyte and Platelet Ratio, Procalcitonin, and Total Leucocyte Count as indicators of prognostic outcome in septic p…

Egypt290 participantsStarted 2024-09-20

Treatment: Neutrophils to Lymphocytes and Platelets ratio (N/LP)

RecruitingNot Applicable

NCT05280132

Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD E…

COPD is a common chronic disease. Its natural course is characterized by Acute exacerbations (AE). This may require hospitalization or even ICU/RESUSCITATION ad…

France204 participantsStarted 2022-12-08

Treatment: Personalized antibiotic treatment, Usual antibiotic treatment

RecruitingNot Applicable

NCT03905239

A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction

Adhesion-related small bowel obstruction is a common digestive emergency that can be managed either conservatively or surgically. However, the choice between th…

France488 participantsStarted 2019-04-01

Treatment: algorithm

All recent trials (100 shown)

CompletedNot Applicable

NCT05463406

Procalcitonin and Lung Ultrasonography Guided Antibiotherapy in Emergency Departments

Acute respiratory infections are a common reason of attendance at emergency departments. It is also the main reason of unnecessary antibiotic prescription. Anti…

Switzerland1,407 participantsStarted 2022-12-05

Treatment: The PLUS algorithm, Usual care

CompletedPhase 2

NCT04983901

PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN

This phase II trial studies the effect of imipenem-relebactam in treating patients with cancer who have a fever due to low white blood cell counts (febrile neut…

United States100 participantsStarted 2021-09-14

Treatment: Imipenem/Cilastatin/Relebactam, Cefepime

Procalcitonin

Trial phase breakdown

Trial status

Actively recruiting — 9 trials

Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis

Prediction of Mortality and Morbidity After Hip Fracture Using Monocyte Distribution Width (MDW)

KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use - Comparing Procalcitonin Kinetics-guided and Absolute Pr…

Neutrophils to Lymphocytes and Platelets Ratio, Procalcitonin, and Total Leucocytic Count as Indicators of Prognostic Ou…

Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD E…

A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction

All recent trials (100 shown)

Procalcitonin and Lung Ultrasonography Guided Antibiotherapy in Emergency Departments

PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN

Trial phase breakdown

Trial status

Actively recruiting — 9 trials

Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis

Prediction of Mortality and Morbidity After Hip Fracture Using Monocyte Distribution Width (MDW)

KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use - Comparing Procalcitonin Kinetics-guided and Absolute Pr…

Neutrophils to Lymphocytes and Platelets Ratio, Procalcitonin, and Total Leucocytic Count as Indicators of Prognostic Ou…

Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD E…

A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction

All recent trials (100 shown)

Procalcitonin and Lung Ultrasonography Guided Antibiotherapy in Emergency Departments

PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN

Inflammatory Markers After COloRectal Surgery)

Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the MODIFY Trial)

Evaluation of the Clinical Relationship Between Procalcitonin Level and Bacteremia Agent in Intensive Care Unit Patients

Use of Lactate-to-Albumin, CRP-to-Albumin, and Procalcitonin-to-Albumin Ratios to Predict Mortality in ICU Patients

Procalcitonin and Threatened Premature Delivery

Procalcitonin and Duration of AntiBiotherapy In Late Onset Sepsis of Neonate

Evaluating the Accuracy of Multiple Blood Tests to Diagnose Sepsis in Adult Burn Patients

Effect of Lactiplantibacillus Plantarum DAD-13 on Inflammatory Markers in ICU Sepsis Patients

Comparison Between the Progostic Value of the Procalcitonin and the Platelet/Total Leukocytic Count Ratio in Sepsis

Pneumonia Pathogens' Virulence Factors, Patient Inflammatory Markers, and Their Associations With Outcomes

Procalcitonin Aided Antimicrobial Therapy vs Standard of Care

PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration

Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized…

PROcalcitonin Impact on Antibiotic Reduction, adverSe Events and AVoidable healthcarE Costs (ProSAVE): A RCT

Procalcitonin and Antimicrobial Utilization in Critically Ill Cancer Patients with Sepsis

PCT Guided Stopping of Antibiotic Therapy in Children With Sepsis

SOFA Score with Serum Procalcitonin Versus SOFA Score with Neutrophil/lymphocyte Ratio in Predicting Sepsis and Clinical…

Impact on PCT+ FilmArray RP2 Plus Use in LRTI Suspicion in Emergency Department