Weakness Acquired in the ICU

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Weakness Acquired in the ICU trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 10 trials

RecruitingNot Applicable

NCT04658498

Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU

Mechanical ventilation is a life-saving treatment frequently applied in intensive care unit (ICU). Nonetheless, by putting at rest the respiratory muscles, it c…

Belgium90 participantsStarted 2023-02-01

Treatment: Procedure: Usual Care (UC), Procedure: UC + HI-IMT

RecruitingNot Applicable

NCT06700694

Technology-Assisted Early Mobilization Program Among Patients in the Intensive Care Units

This single-blind, three-group parallel randomized controlled trial will involve 138 patients with critical illness, randomly assigned at a 1:1:1 ratio to the t…

Taiwan138 participantsStarted 2025-03-04

Treatment: Technology-assisted, family-engaged in-bed activities, Protocol-oriented early mobilization program

RecruitingNot Applicable

NCT06184945

Behavioral Economic & Staffing Strategies in the ICU

The overarching goal of this study is to support the "real world" assessment of strategies used to foster adoption of several highly efficacious evidence-based…

United States8,100 participantsStarted 2024-07-01

Treatment: Realtime audit and feedback, RN Implementation Facilitator

RecruitingNot Applicable

NCT06499389

Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients

Difficult ventilatory weaning is associated with a 20% mortality rate. 40% of these patients will develop intensive care unit (ICU)-acquired neuromyopathy, asso…

France50 participantsStarted 2025-03-18

Treatment: Systematic and early intensive instrumental respiratory physiotherapy for patients undergoing difficult ventilatory weaning, Protocolized standard-of-care respiratory physiotherapy

RecruitingNot Applicable

NCT03753412

Recovery From ICUAW Following Severe Respiratory and Cardiac Failure

To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra…

United Kingdom100 participantsStarted 2019-04-09

RecruitingNot Applicable

NCT06973746

Effect of the "Sitting Out of Bed in an Arm-chair Position" in ICU on Functional Recovery Among Ventilated Patients

Chair positioning is one of a series of early mobilization techniques. At present, this technique, which involves moving a patient out of the resuscitation bed,…

France150 participantsStarted 2025-07-04

Treatment: sitting out of bed in an arm-chair position

All recent trials (52 shown)

By InvitationNot Applicable

NCT07150650

Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level

Acquired weakness (AW) is a common complication among patients in the Intensive Care Unit (ICU). It is a systemic muscle weakness and dysfunction associated wit…

China500 participantsStarted 2026-03-01

Treatment: ICU-AW

Active — Not RecruitingNot Applicable

NCT07361419

Metabolic Response to Supine Physiotherapy in Mechanically Ventilated ICU Patients

Critically ill patients who require mechanical ventilation frequently experience rapid loss of muscle mass and physical function during their stay in the intens…

Spain40 participantsStarted 2026-02-01

Treatment: Supine Physiotherapy Session

Weakness Acquired in the ICU

Trial phase breakdown

Trial status

Actively recruiting — 10 trials

Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU

Technology-Assisted Early Mobilization Program Among Patients in the Intensive Care Units

Behavioral Economic & Staffing Strategies in the ICU

Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients

Recovery From ICUAW Following Severe Respiratory and Cardiac Failure

Effect of the "Sitting Out of Bed in an Arm-chair Position" in ICU on Functional Recovery Among Ventilated Patients

All recent trials (52 shown)

Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level

Metabolic Response to Supine Physiotherapy in Mechanically Ventilated ICU Patients

Trial phase breakdown

Trial status

Actively recruiting — 10 trials

Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU

Technology-Assisted Early Mobilization Program Among Patients in the Intensive Care Units

Behavioral Economic & Staffing Strategies in the ICU

Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients

Recovery From ICUAW Following Severe Respiratory and Cardiac Failure

Effect of the "Sitting Out of Bed in an Arm-chair Position" in ICU on Functional Recovery Among Ventilated Patients

All recent trials (52 shown)

Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level

Metabolic Response to Supine Physiotherapy in Mechanically Ventilated ICU Patients

MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients

Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes

Using Continuous Passive Motion to Prevent Ankle Problems in ICU Patients

TESTO-TRIAL: Use of Testosterone in Critically Ill Patients

Detection of Neuromuscular Complications in Critically Ill Patients

Data Analysis and Physical Function Evaluation Index Development for Early Diagnosis and Monitoring of ICU-acquired Weak…

The Effects of Virtual Reality in Intensive Care Patients

Ultrasound Measurement of Quadriceps Shortening During Neuromuscular Electrical Stimulation in Critically Ill Patients

Efficacy and Safety of Administration of High Levels of Protein to Critically Ill Patients.

Neuromuscular Electrical Stimulation in ICU Patients

PRotEin Provision in Critical IllneSs

The Use of Musculoskeletal Ultrasound for the Detection of ICU-Acquired Weakness

Safety and Efficacy of the MyokinE100 (CL-EMS Alpha) Device in Inducing Visible Muscle Contraction in Healthy Volunteers

Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts

Evaluation of FDY-5301 in Major Trauma Patients in ICU

5 Years Quality of Life and Early Mobilization in ICU

The Effect of Inspiratory Muscle Training on Diaphragmatic Function in Mechanically Ventilated Patients

How COVID-19 Effects to Muscle Mass Change ın ICU?