Vulvar HSIL

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Vulvar HSIL trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 2

NCT06075264

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HS…

This is a phase II double-blind, placebo-controlled study of artesunate ointment for the treatment of HPV-associated vulvar HSIL (usual type vulvar intraepithel…

United States27 participantsStarted 2023-12-06

Treatment: Artesunate ointment, Placebo ointment

All recent trials (15 shown)

Not Yet RecruitingPhase 1

NCT06233331

Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV

The goal of this study is to test the maximum tolerated dose of ACU-D1 in HIV-positive people with HPV-associated vulvar and perianal lesions. The main question…

United States9 participantsStarted 2026-06

Treatment: Dose Level 1 ACU-D1 ointment, Dose Level 2 ACU-D1 ointment

CompletedPhase 1/2

NCT02858310

E7 TCR T Cells for Human Papillomavirus-Associated Cancers

Background: Human papillomavirus (HPV) can cause cervical, throat, anal, and genital cancers. Cancers caused by HPV have an HPV protein called E7 inside of the…

United States224 participantsStarted 2017-01-27

Treatment: E7 TCR cells, Aldesleukin

Vulvar HSIL

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HS…

All recent trials (15 shown)

Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV

E7 TCR T Cells for Human Papillomavirus-Associated Cancers

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HS…

All recent trials (15 shown)

Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV

E7 TCR T Cells for Human Papillomavirus-Associated Cancers

Trial to Evaluate Nonavalent HPV Vaccine as a Secondary Prevention in Patients Treated for Human Papilloma Virus Related…

Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia

Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vagin…

IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Ne…

Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN)

Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)

Adjuvant Nonavalent HPV Vaccination in Women Treated for Vulvar HSIL

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV…

Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

ICVT in HPV-induced Genital Lesions of Immunocompromised and Immunocompetent Patients