Trachea Diseases

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Trachea Diseases trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 12 trials

RecruitingNot Applicable

NCT04217603

Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC

The purpose of this protocol is to perform a prospective, randomized, double-blinded, pacebo-controlled clinical trial to determine the influence of a non-invas…

United States32 participantsStarted 2023-03-01

Treatment: Continuous positive airway pressure (CPAP) device, Sham-continuous positive airway pressure (CPAP) device

RecruitingNot Applicable

NCT06406452

Bioresorbable Airway Splint Pivotal Clinical Trial

The purpose of this study is to learn if a three-dimensional (3D) printed airway splint device made to hold open a collapsing airway is a safe and effective tre…

United States35 participantsStarted 2025-01-07

Treatment: Bioresorbable Tracheobronchial Splint

RecruitingPhase 1/2

NCT03556228

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

This is a multicenter, open-label, Phase 1/2 study of orally administered VMD-928 monotherapy and in combination with pembrolizumab in adult subjects with advan…

United States242 participantsStarted 2018-06-08

Treatment: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg)

RecruitingPhase 1

NCT06085209

Cryospray Therapy for Benign Airway Stenosis

This is a clinical evaluation to assess the effectiveness of cryospray therapy used in addition to current standard of care endoscopic therapies in preventing s…

United States12 participantsStarted 2023-10-12

Treatment: The truFreeze Spray Cryotherapy, Ballon dilation

RecruitingNot Applicable

NCT06935110

Feasibility of Tracheobronchial Defect Reconstruction Using Allogenic Aortic Patch

The investigators investigate the feasibility and safety of using cryopreserved aortic patches for tracheal or bronchial defect repair.

Taiwan10 participantsStarted 2025-09-15

Treatment: Cryopreserved aortic patch

RecruitingNot Applicable

NCT07258784

RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis

Benign tracheal stenosis is a rare but potentially life-threatening condition, typically resulting from fibroinflammatory scarring. It can be secondary to iatro…

United States10 participantsStarted 2025-09-11

Treatment: Biopsy or surgery

All recent trials (100 shown)

TerminatedNot Applicable

NCT04719845

DilAtation Versus Endoscopic Laser Resection in Simple Benign trAcheal sTEnosis

Multicenter randomized controlled trial comparing endoscopic laser resection vs dilatation in benign tracheal stenosis.

Canada, France108 participantsStarted 2021-03-17

Treatment: Endoscopic laser resection, Dilatation

Not Yet RecruitingNot Applicable

NCT07191860

Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis

The OXYGEN-RCT trial is a randomized, controlled, double blinded, prospective, multi-center trial to demonstrate the safety and efficacy in adult benign central…

United States200 participantsStarted 2026-03-01

Treatment: The Airiver Pulmonary drug-coated balloon (DCB) dilation, Commercial airway balloon dilation

Trachea Diseases

Trial phase breakdown

Trial status

Actively recruiting — 12 trials

Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC

Bioresorbable Airway Splint Pivotal Clinical Trial

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

Cryospray Therapy for Benign Airway Stenosis

Feasibility of Tracheobronchial Defect Reconstruction Using Allogenic Aortic Patch

RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis

All recent trials (100 shown)

DilAtation Versus Endoscopic Laser Resection in Simple Benign trAcheal sTEnosis

Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis

Trial phase breakdown

Trial status

Actively recruiting — 12 trials

Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC

Bioresorbable Airway Splint Pivotal Clinical Trial

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

Cryospray Therapy for Benign Airway Stenosis

Feasibility of Tracheobronchial Defect Reconstruction Using Allogenic Aortic Patch

RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis

All recent trials (100 shown)

DilAtation Versus Endoscopic Laser Resection in Simple Benign trAcheal sTEnosis

Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis

Everolimus Trial in Laryngotracheal Stenosis

Transcriptomic Profile Changes in Benign Tracheal Stenosis: Wedge Resection vs. Radial Incision

Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children

Evaluation of Effectiveness of the Treatment After Repeated Administration of Klacid®SR

Voice Quality Analysis of Patients With Laryngotracheal Stenosis

Airway Stents for Excessive Dynamic Airway Collapse

CT-Based Scoring System to Predict Surgical Need in Tracheal Stenosis (TSMAS Study)

Comparison of Pre-procedure Lignocaine Spray Versus Spray-as-you-go for Topical Airway Anesthesia in Flexible Bronchosco…

The Novel Special Light for Endotracheal/Bronchial Lesions.

Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam

Primary Posterior Tracheopexy Prevents Tracheal Collapse

Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair

Post Market Clinical Study - Evolution® Esophageal Stent Systems, Europe: Fully and Partially Covered

Prediction of Weaning Outcome From Mechanical Ventilation Using Ultrasound

Outcomes of Using LNMES on Tracheostomized Children

Oxygen Insufflation Via Flexible Scope

Ultrasound Assessment of the Larynx and Trachea in the Neonatal Period

High-flow Nasal Oxygen During Rigid Bronchoscopy Under General Anesthesia: a Randomized Controlled Trial