Sickle Cell Crisis
Clinical trial pipeline · Data from ClinicalTrials.gov
See which Sickle Cell Crisis trials may be worth asking aboutClinical trial pipeline · Data from ClinicalTrials.gov
See which Sickle Cell Crisis trials may be worth asking aboutNorth America
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This is a phase 2a, global, multicenter, randomized, double-blind, placebo-controlled study investigating the safety of anumigilimab administered subcutaneously…
This study is not a treatment protocol and no experimental treatments are involved. Study participants may be seen as needed for clinical, translational and bas…
A phase III, multi-center, randomized, placebo-controlled, double-blind study to assess efficacy and safety of crizanlizumab (5 mg/kg) versus placebo, with or w…
The purpose of the study is to determine whether adding lidocaine to standard of care in pain management during severe vaso-occlusive crisis has an effect on th…
This is a multi-center multi-national rollover study to allow continued access to crizanlizumab for patients with sickle cell disease (SCD) who are on crizanliz…
Acute vaso-occlusive crisis (VOC) is the most common complication in patients with sickle cell disease (SCD) and pain related to VOC is often inadequately treat…
Background: Sickle cell disease (SCD) is an inherited blood disorder. The disease affects the ability of red blood cells to carry oxygen; this in turn can inju…
The purpose of this study is to compare the efficacy and safety of 2 doses of crizanlizumab (5.0 mg/kg and 7.5 mg/kg) versus placebo in adolescent and adult sic…