Severe Trauma Patient

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Severe Trauma Patient trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

RecruitingNot Applicable

NCT07560631

SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury

Objective: This prospective interventional study introduces "SeeMe," an automated, high-resolution computer vision platform designed to objectively quantify mic…

United States80 participantsStarted 2026-03-30

Treatment: SeeMe Multimodal Auditory Command Protocol

RecruitingPhase 4

NCT07168421

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

Limiting perioperative tachycardia (aiming for a heart rate \<90 beats per minute throughout the perioperative period) using the ultra-short acting beta-blocker…

Switzerland114 participantsStarted 2026-04-24

Treatment: Landiolol

RecruitingPhase 3

NCT06337838

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial

The BRACKETS pilot study is a multicentre, prospective, randomized controlled trial of prophylactic preoperative tranexamic acid (TXA) versus placebo and, using…

Canada100 participantsStarted 2025-06-09

Treatment: Desmopressin Injectable Solution, Tranexamic Acid Injectable Product

RecruitingNot Applicable

NCT05635929

Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients…

The use of a novel topical mucosa composition (XCM-OM118) comprising 2-(trimethylazaniumyl) acetate; (2R,3R,4S)-pentane-1,2,3,4,5-pentol; Hexadecanoic acid; (9Z…

Spain63 participantsStarted 2022-10-11

Treatment: XCM-OM118 Composition comprising olive oil, betaine and xylitol

RecruitingPhase 2

NCT06065046

Baricitinib for Moderate and Severe Traumatic Intracerebral Hemorrhage/Contusions

The purpose of the present study is to study the effect of baricitinib administration on outcome of participants with moderate and severe traumatic intracerebra…

China100 participantsStarted 2023-11-24

Treatment: Baricitinib 4 MG, Standard treatment

RecruitingNot Applicable

NCT07351149

Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery

This project aims to conduct an international, prospective, multicentre, observational study to determine the incidence of Postoperative Acute Kidney Injury (PO…

Australia, Brazil +2 more2,000 participantsStarted 2026-03-01

All recent trials (100 shown)

Not Yet RecruitingNot Applicable

NCT07558265

WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department

The purpose of this clinical trial is to determine the best initial non-invasive respiratory support (NIRS) strategy for adults who present to the emergency dep…

United States500 participantsStarted 2026-07

Treatment: Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen

Not Yet RecruitingPhase 2

NCT07567768

Continuous vs Bolus Neuromuscular Blockade Regimens in Moderate to Severe Hypoxemic Respiratory Failure and ARDS (COBRA)

Current clinical guidelines, such as those from the Surviving Sepsis Campaign and ARDSNet, recommend short-term NMBA use for patients with moderate to severe AR…

Location not specified100 participantsStarted 2027-01-01

Treatment:

Severe Trauma Patient

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial

Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients…

Baricitinib for Moderate and Severe Traumatic Intracerebral Hemorrhage/Contusions

Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery

All recent trials (100 shown)

WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department

Continuous vs Bolus Neuromuscular Blockade Regimens in Moderate to Severe Hypoxemic Respiratory Failure and ARDS (COBRA)

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial

Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients…

Baricitinib for Moderate and Severe Traumatic Intracerebral Hemorrhage/Contusions

Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery

All recent trials (100 shown)

WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department

Continuous vs Bolus Neuromuscular Blockade Regimens in Moderate to Severe Hypoxemic Respiratory Failure and ARDS (COBRA)

Feasibility of a Digital Goals-of-Care Decision Aid for Clinicians and Families of Patients With SABI

Clinical Trial of Lyophilized Powder for Inhalation of Recombinant Human Keratinocyte Growth Factor-2 (Rh-KGF-2) in The…

Intermediate Versus Standard Dose Enoxaparin to Prevent Venous Thromboembolism in Severe Trauma Patients: a Multicenter…

MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients

Integration of a Robotic Platform for Clinical Monitoring of Patients With Severe Acquired Brain Injury in High-Intensit…

Efficacy and Safety of Early Use PCC in Severe Trauma

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing…

Transcutaneous Electrical Acupoint Stimulation at Jing-Well Points for Disorders of Consciousness

Multicentre Study: Adherence to the Severe Trauma Patients Pathway in PACA Region

ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE

SurgiPerito Trial: High-Purity Type-I Collagen for Peritoneal Reconstruction After Cytoreductive Surgery

SecondarY Prevention and maNagement of Myocardial Injury aftER Noncardiac surGerY (SYNERGY) Pilot Trial

Effects of Recombinant Human Growth Hormone in Elderly Patients With Moderate to Severe Acute Brain Injury (GH-ABI-RCT)

Myocardial Injury in Noncardiac Surgery in Sweden

Assessment of the Benefit of an Inclusive Health Organization on the Prognosis of Severe Trauma Patients

TRISS as a Predictor of Trauma Patient Outcomes

Optimized Strict Fluid Management Helps Improve Endpoints After Liver Dissection

Microdialysis and Jugular Bulb Glucose Profiles During Hyperglycaemic Clamping in Patients With Severe Acute Brain Injur…