Prolonged Grief Disorder

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Prolonged Grief Disorder trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 6 trials

RecruitingEarly Phase 1

NCT06724289

Psilocybin for Prolonged Grief Disorder

The primary purpose of this study is to explore the feasibility of conducting a clinical trial on the effects of psilocybin for individuals with prolonged grief…

United States12 participantsStarted 2026-03

Treatment: Psilocybin 25 mg, Functional Magnetic Resonance Imaging (fMRI)

RecruitingNot Applicable

NCT06932120

Technology-supported Interventions for Prolonged Grief Disorder (PGD)

The main aim of this project is to test the efficacy of two formats of delivering an internet- based treatment(GROw) for Prolonged Grief Disorder (PGD) in order…

Spain141 participantsStarted 2025-11-10

Treatment: Internet-based treatment (GROw) combined with face-to-face videoconferencing sessions with a therapist in BF-GROw group, Internet-based treatment (GROw) supported by the App developed which contains the EMA and EMI tools in iGROw group.

RecruitingNot Applicable

NCT06854757

Families Left Behind

The United States is facing unprecedented rates of drug overdose deaths, profoundly impacting millions of families who are left to navigate their grief. Those b…

United States340 participantsStarted 2025-06-13

Treatment: RIVER, Enhanced care as usual

RecruitingNot Applicable

NCT06733974

A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department

In France, a study has reported that about 0.2% of patients visiting the ED died in the ED. A large survey of 145 EDs in 3 French speaking countries has reporte…

France924 participantsStarted 2025-06-04

Treatment: Multi-faceted Intervention

RecruitingNot Applicable

NCT06017765

Coping After Loss Through Mindfulness in Adults With Prolonged Grief Disorder

The goal of this clinical trial is to pilot the effectiveness of an 8-week standardized Mindfulness Training program to decrease the psychiatric and somatic sym…

France30 participantsStarted 2023-08-01

Treatment: Meditation Training, Waitlist

RecruitingNot Applicable

NCT06667674

A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCT

The goal of this clinical trial is to evaluate the effectiveness of internet-delivered Cognitive Behavioral Therapy (iCBT) in reducing symptoms of prolonged gri…

Sweden270 participantsStarted 2025-04-23

Treatment: iCBT for prolonged grief, Active control

All recent trials (42 shown)

Not Yet RecruitingPhase 2/3

NCT07537894

Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation

People seeking second-trimester dilation and evacuation (D\&E) procedures are often facing profoundly challenging circumstances, including desired pregnancies c…

United States100 participantsStarted 2026-07

Treatment: Dexmedetomidine (IV) 0.5 mcg/kg, Placebo

By InvitationNot Applicable

NCT07318090

F-PGT - Prolonged Grief Treatment for Families Affected by Suicide

This pilot open trial is being done to better understand the needs of families who have lost a parent to suicide at least a year ago and who have children ages…

United States30 participantsStarted 2025-12-17

Treatment: F-PGT

Prolonged Grief Disorder

Trial phase breakdown

Trial status

Actively recruiting — 6 trials

Psilocybin for Prolonged Grief Disorder

Technology-supported Interventions for Prolonged Grief Disorder (PGD)

Families Left Behind

A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department

Coping After Loss Through Mindfulness in Adults With Prolonged Grief Disorder

A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCT

All recent trials (42 shown)

Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation

F-PGT - Prolonged Grief Treatment for Families Affected by Suicide

Trial phase breakdown

Trial status

Actively recruiting — 6 trials

Psilocybin for Prolonged Grief Disorder

Technology-supported Interventions for Prolonged Grief Disorder (PGD)

Families Left Behind

A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department

Coping After Loss Through Mindfulness in Adults With Prolonged Grief Disorder

A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCT

All recent trials (42 shown)

Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation

F-PGT - Prolonged Grief Treatment for Families Affected by Suicide

Prolonged Grief Disorder (PGD) Diagnosis in Older Adults: Physicians' Knowledge and Practice

Effectiveness of a Brief Psychological Intervention (P-CRP) for Complex Trauma and Loss

Understanding and Responding to Grief-Related Needs: A Differentiated Community Approach

Iyengar Yoga for Prolonged Grief Disorder

Emotion-Focused Therapy in the Treatment of Prolonged Grief Disorder

Adolescent Suicide Loss Survivors Grief Intervention Group

Diagnostic Tools for Identifying Prolonged Grief

Cognitive Behavioural Therapy for Complicated Grief Reactions in Old Age

Naltrexone for Prolonged Grief Disorder

Transcranial Magnetic Stimulation to Treat Prolonged Grief Disorder

Building and Sustaining Interventions for Children: Task-sharing Mental Health Care in Low-resource Settings

Oxytocin and Approach-avoid in Grief

Feasibility and Efficacy of Individual SH+ Intervention

Naltrexone Treatment for Prolonged Grief Disorder (PGD)

Web Based Patient Tutorial on Prolonged Grief

Empower-Grief: A Study on a Selective Intervention to Prevent Prolonged Grief Disorder

Prolonged Grief and Perception of Femininity in Gynecological Cancer Patients

Tele-based Psychological Emotional Support for Informal CARegivers of COVID-19 Patients in Intensive Care