Primary Sjögren's Syndrome (pSS)

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Primary Sjögren's Syndrome (pSS) trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

RecruitingPhase 2

NCT05113004

New Clinical End-points in Patients With Primary Sjögren's Syndrome

There are no approved treatments for pSS and the clinical endpoints currently used in clinical trials are inadequate to capture all aspects of the disease that…

France300 participantsStarted 2022-01-20

Treatment: Hydroxychloroquine 400mg/d, Leflunomide 20mg/d

RecruitingNot Applicable

NCT03040583

The ASSESS National Multi-center Prospective Cohort

The ASSESS national multi-center prospective cohort (Assessment of Systemic complications (Signs) and Evolution in Sjögren's Syndrome "SS") was set up in 2006 t…

France395 participantsStarted 2016-09

Treatment: No intervention

RecruitingNot Applicable

NCT03681964

Diagnostic Suspicion of Primitive Syndrome Sjögren's : Brest Cohort

This study aims to evaluate the diagnosis performance of several item used for the classification, the diagnosis and the prognostic of pSS (primary Sjogren synd…

France100 participantsStarted 2015-09-28

All recent trials (19 shown)

CompletedPhase 2

NCT06203457

Open-Label Extension Study to Evaluate the Safety of Efgartigimod in Adult Patients With Primary Sjögren's Syndrome

Efgartigimod has the potential to improve disease manifestations by the reduction of IgG autoantibodies in Sjogren's Syndrome (SjD or pSS). This open-label exte…

Belgium, Hungary, Poland24 participantsStarted 2023-11-29

Treatment: Efgartigimod

CompletedPhase 2/3

NCT01782235

Efficacy of Tocilizumab in Primary Sjögren's Syndrome.

Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterized by lymphocytic infiltration leading to destruction of acinar and ductal cells an…

France110 participantsStarted 2013-07-24

Treatment: Tocilizumab, Placebo

Primary Sjögren's Syndrome (pSS)

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

New Clinical End-points in Patients With Primary Sjögren's Syndrome

The ASSESS National Multi-center Prospective Cohort

Diagnostic Suspicion of Primitive Syndrome Sjögren's : Brest Cohort

All recent trials (19 shown)

Open-Label Extension Study to Evaluate the Safety of Efgartigimod in Adult Patients With Primary Sjögren's Syndrome

Efficacy of Tocilizumab in Primary Sjögren's Syndrome.

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

New Clinical End-points in Patients With Primary Sjögren's Syndrome

The ASSESS National Multi-center Prospective Cohort

Diagnostic Suspicion of Primitive Syndrome Sjögren's : Brest Cohort

All recent trials (19 shown)

Open-Label Extension Study to Evaluate the Safety of Efgartigimod in Adult Patients With Primary Sjögren's Syndrome

Efficacy of Tocilizumab in Primary Sjögren's Syndrome.

A Study of Yiqi Yangyin Formula in the Treatment of Primary Sjogren's Syndrome

A Study of the Safety and Effectiveness of Efgartigimod in Patients With Primary Sjögren's Syndrome (pSS)

Current Therapy in Primary Sjogren's Syndrome

Artificial Intelligence Based Models for Primary Sjögren's Syndrome Diagnosis

Therapeutic Effect of Upadacitinib in Primary Sjögren's Syndrome

Pilot Trial of Ustekinumab for Primary Sjögren's Syndrome

A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 12 Weeks in Adults With Active Primary Sjögren…

Clinical Study to Investigate the Efficacy of Orally Administered SA001 in Patients With Primary Sjögren's Syndrome

Reliability, Validity of the Turkish Version of the Primary Sjögren Syndrome Quality of Life (PSS-QoL) Questionnaire

A PH I Pilot Imaging Study to Evaluate Molecular Imaging Methods in HVs and pSS Pts

Adelphi Primary Sjogren's Syndrome (pSS) Disease Specific Programme (DSP)

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Proof of Mechanism of GSK2618960 in Primary Sjögren…

LAMELLEYE for the Treatment of Dry Eye Symptoms in pSS Patients

Allogeneic Mesenchymal Stem Cells Transplantation for Primary Sjögren's Syndrome (pSS)