Peptic Ulcer Disease

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Peptic Ulcer Disease trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 31 trials

RecruitingNot Applicable

NCT07495020

The Transit Bipartition With the Use of a Metallic Anastomosis Clip and Circular Fundocorporeal Gastroplication

This study evaluates a new surgical device - the Metallic Anastomotic Clip (MAC) - for performing a laparoscopic bypass gastroenteroanastomosis with entero-ente…

Kazakhstan90 participantsStarted 2026-04-30

Treatment: Laparoscopic transit bipartition with Metallic Anastomotic Clip and Circular Fundocorporeal Gastroplication, Laparoscopic transit bipartition (gastroenteroanastomosis and entero-enteric anastomosis) use the Metallic Anastomotic Clip and with sleeve gastrectomy

RecruitingPhase 4

NCT07537634

Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication

The goal of this clinical trial is to compare the efficacy and safety of vonoprazan-based levofloxacin-containing triple therapy with esomeprazole-based levoflo…

Bangladesh80 participantsStarted 2026-04-15

Treatment: vonoprazan-based triple therapy (VAL regimen), Esomeprazole-based triple therapy (EAL regimen)

RecruitingPhase 4

NCT05799105

OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers

The goal of this clinical trial is to identify the most effective way to take acid-blocking medications to treat stomach ulcers in patients who have undergone g…

United States122 participantsStarted 2023-03-14

Treatment: Omeprazole 40 milligrams

RecruitingPhase 4

NCT05582174

PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers

Vonoprazan (VPZ), an oral potassium-competitive acid blocker (P-CAB) has emerged as an alternative potent acid-suppressant.It has a faster onset of action in 1…

China594 participantsStarted 2023-05-18

Treatment: Vonoprazan, esomeprazole

RecruitingPhase 1

NCT07385235

Compare and Evaluate the Safety and PK Data of a Single Dose Administration of 'AD-115A' or 'AD-1151'

The study compare and evaluate the safety and pharmacokinetic characteristics of a single dose administration of 'AD-115A' or 'AD-1151' in healthy adults.

South Korea46 participantsStarted 2026-01-27

Treatment: AD-115A, AD-1151

RecruitingPhase 4

NCT07344506

CURE-H. Pylori: A Trial on the Combination of Anti-Ulcerants and Levofloxacin-Based Therapy for Helicobacter Pylori Erad…

This study, titled CURE-H. Pylori, is a three-arm, parallel-group, open-label, randomized controlled trial designed to evaluate the effectiveness of Dexlansopra…

Pakistan942 participantsStarted 2025-05-01

Treatment: Arm 1: Dexlansoprazole + Levofloxacin-Based Triple Therapy, Arm 2: Lansoprazole + Levofloxacin-Based Triple Therapy

All recent trials (100 shown)

CompletedNot Applicable

NCT00001254

Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome

This protocol concerns the approach to the localization, diagnosis of MEN1 and management of the tumor and the tissue samples in patients with Zollinger-Ellison…

United States273 participantsStarted 1991-10-29

Not Yet RecruitingNot Applicable

NCT07558707

Fexuclue for Prevention of NSAIDs-Induced Peptic Ulcer in Real-World Practice

This study is a prospective, multi-center, observational study to evaluate the efficacy and safety of Fexuclue Tablet 20 mg in patients requiring prevention of…

South Korea7,000 participantsStarted 2026-04-30

Not Yet RecruitingPhase 4

NCT07533266

Peptic Ulcer Disease

Trial phase breakdown

Trial status

Actively recruiting — 31 trials

The Transit Bipartition With the Use of a Metallic Anastomosis Clip and Circular Fundocorporeal Gastroplication

Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication

OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers

PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers

Compare and Evaluate the Safety and PK Data of a Single Dose Administration of 'AD-115A' or 'AD-1151'

CURE-H. Pylori: A Trial on the Combination of Anti-Ulcerants and Levofloxacin-Based Therapy for Helicobacter Pylori Erad…

All recent trials (100 shown)

Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome

Fexuclue for Prevention of NSAIDs-Induced Peptic Ulcer in Real-World Practice

Trial phase breakdown

Trial status

Actively recruiting — 31 trials

The Transit Bipartition With the Use of a Metallic Anastomosis Clip and Circular Fundocorporeal Gastroplication

Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication

OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers

PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers

Compare and Evaluate the Safety and PK Data of a Single Dose Administration of 'AD-115A' or 'AD-1151'

CURE-H. Pylori: A Trial on the Combination of Anti-Ulcerants and Levofloxacin-Based Therapy for Helicobacter Pylori Erad…

All recent trials (100 shown)

Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome

Fexuclue for Prevention of NSAIDs-Induced Peptic Ulcer in Real-World Practice

Study to Evaluate the Efficacy and Safety of Fexuprazan in Prevention of NSAIDs Induced Peptic Ulcer

Pharmacist-Driven Stress Ulcer Prophylaxis Minimization in the Intensive Care Unit

Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing

FundoRing Roux-en-Y Gastric Bypass Versus FundoRing One Anastomosis Gastric Bypass

Predicting Peptic Complications Using H. Pylori Serology and Gastric Ultrasound

A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal Ulcer

Efficacy and Safety of Esomeprazole 40 mg IV in Post-Surgical Patients Admitted to the ICU

The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients

Comparative Effectiveness of Triple Versus Quadruple Therapy in the Treatment of Helicobacter Pylori Induced Gastritis

Outcome Analysis of POEM and Endoluminal Therapies

Endoscopic Metabolic and Bariatric Therapies

Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD

The Use of Indocyanine Green to Visualize Blood Flow to the Gastrojejunostomy During Bariatric Surgery.

The Study Compare and Evaluate the Safety and PK Data of a Single Dose Administration of 'AD-115A' or 'AD-1151'

Early Oral Feeding Versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair

Clinical Evaluation of a 14day Modified Bismuth Quadruple Therapy for the Eradication of Helicobacter Pylori in a High C…

Omitting Drains After Repair of Peptic Ulcer Perforations

Ulcer Pomegranate Muffins