Necator Americanus Infection

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Necator Americanus Infection trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 1

NCT01940757

Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae

An experimental hookworm infection model is being developed to provide early proof-of-concept that a hookworm vaccine targeting the blood-feeding pathway of adu…

United States35 participantsStarted 2015-01

Treatment: Necator americanus Hookworm Larvae

All recent trials (20 shown)

Active — Not RecruitingNot Applicable

NCT05372068

Cement flooRs AnD chiLd hEalth (CRADLE)

This randomized trial in rural Bangladesh will measure whether installing concrete floors in households with soil floors reduces child enteric infection. The tr…

Bangladesh800 participantsStarted 2023-09-24

Treatment: Concrete household floor

CompletedPhase 1

NCT02143518

Safety and Immunogenicity Study of Na-GST-1 With or Without CpG

Na-GST-1 is a protein expressed during the adult stage of the hookworm life cycle that is thought to play a role in the parasite's degradation of host hemoglobi…

United States24 participantsStarted 2014-10

Treatment: Na-GST-1/Alhydrogel®, CpG 10104

Necator Americanus Infection

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae

All recent trials (20 shown)

Cement flooRs AnD chiLd hEalth (CRADLE)

Safety and Immunogenicity Study of Na-GST-1 With or Without CpG

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae

All recent trials (20 shown)

Cement flooRs AnD chiLd hEalth (CRADLE)

Safety and Immunogenicity Study of Na-GST-1 With or Without CpG

Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children

Immune Responses in the Skin After Hookworm Infection

Establishing a Controlled Human Hookworm Infection Model at Leiden University Medical Center

Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults

Repeated Controlled Human Hookworm Infection

Validation of INSPiRED Innovative Smart Diagnostic Devices for the Detection of Parasites Infections.

Hookworm Therapy for Coeliac Disease

Immunisation, Treatment and Controlled Human Hookworm Infection

Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults

Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana

Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults

The Impact of Anthelmintic Treatment on the Incidence of Diarrheal Disease in Vietnamese School Children

Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivi…

Monitoring the Efficacy of Anthelmintics for the Treatment of Soil Transmitted Helminths P2

Desensitising Celiac Disease Patients With the Human Hookworm

Study to Test Whether Shoes Protect Children Against Hookworm Infection on Pemba Island, Zanzibar

Comparative Efficacy of Different Mebendazole Polymorphs in the Treatment of Soil-transmitted Helminth Infections