Multi-antibiotic Resistance

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Multi-antibiotic Resistance trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 12 trials

RecruitingPhase 2

NCT05835206

Further MT for Antibiotic-Resistant Bacterial Colonization

The purpose of this study is to better understand the effectiveness and safety of microbiome therapies (MT) as a treatment for patients with Multidrug Resistant…

United States40 participantsStarted 2024-04-25

Treatment: Microbiome Therapeutic, Placebo

RecruitingNot Applicable

NCT06738771

Antimicrobial Therapy for Difficult-to-treat Pseudomonas Aeruginosa

The primary objective of the ADDICT study is to assess and compare the clinical efficacy of available options for antimicrobial therapy (new beta-lactam/beta-la…

France600 participantsStarted 2025-03-11

RecruitingNot Applicable

NCT07545876

Pneumococcal Carriage, Serotypes, and Antibiotic Resistance in Malaysian Children: A Multi-Centre Study

The goal of this observational study is to determine the prevalence, serotype distribution, and antimicrobial resistance patterns of nasopharyngeal carriage of…

Malaysia600 participantsStarted 2026-04-09

RecruitingPhase 1/2

NCT04759001

FMT for the Decolonization of Carbapenem-resistant Enterobacteriaceae

Rates of antimicrobial resistance are increasing worldwide. There is increasing evidence that physiological gut microbiota is a large reservoir of antibiotic-re…

Italy52 participantsStarted 2021-02-18

Treatment: Donor FMT, Placebo FMT

RecruitingNot Applicable

NCT07134270

Infection Risk Associated With Digestive MDRO Carriage in Hospitalized Patients

This study aims to evaluate the impact of digestive carriage of multidrug-resistant organisms (MDRO) on the risk of healthcare-associated infections in hospital…

Romania400 participantsStarted 2026-01-01

Treatment: MDRO Rectal Screening, 30-Day Telephone Follow-Up

RecruitingPhase 1

NCT07029932

A Phase 1 Study of the Safety and Tolerability of Single and Multiple Ascending Doses of BWC0977 in Healthy Volunteers

The purpose of this study is to assess the safety, tolerability and pharmacokinetics of single and multiple intravenous doses of BWC0977 when administered to he…

Australia48 participantsStarted 2025-10-10

Treatment: BWC0977, Placebo

All recent trials (78 shown)

Not Yet RecruitingNot Applicable

NCT07505446

Characterization of the Synergistic Antibacterial Effect of Verapamil on Bacterial Isolates From Cancer Patients

Multidrug-resistant (MDR) bacteria represent a significant global health challenge, particularly among immunocompromised populations such as cancer patients und…

Location not specified100 participantsStarted 2026-05-01

Treatment: verapamil

Not Yet RecruitingPhase 3

NCT07486024

Feasibility of the Application of a New Six-month Treatment for Multidrug-resistant Tuberculosis (MDR-TB) Patients in Fr…

The FAST-MDR trial is an externally-controlled, multicentre trial with one prospective arm, evaluating the non-inferiority of the effectiveness of BPaLM in the…

France55 participantsStarted 2026-04

Treatment: Bedaquiline Oral Tablet, Bedaquiline Oral Tablet

Multi-antibiotic Resistance

Trial phase breakdown

Trial status

Actively recruiting — 12 trials

Further MT for Antibiotic-Resistant Bacterial Colonization

Antimicrobial Therapy for Difficult-to-treat Pseudomonas Aeruginosa

Pneumococcal Carriage, Serotypes, and Antibiotic Resistance in Malaysian Children: A Multi-Centre Study

FMT for the Decolonization of Carbapenem-resistant Enterobacteriaceae

Infection Risk Associated With Digestive MDRO Carriage in Hospitalized Patients

A Phase 1 Study of the Safety and Tolerability of Single and Multiple Ascending Doses of BWC0977 in Healthy Volunteers

All recent trials (78 shown)

Characterization of the Synergistic Antibacterial Effect of Verapamil on Bacterial Isolates From Cancer Patients

Feasibility of the Application of a New Six-month Treatment for Multidrug-resistant Tuberculosis (MDR-TB) Patients in Fr…

Trial phase breakdown

Trial status

Actively recruiting — 12 trials

Further MT for Antibiotic-Resistant Bacterial Colonization

Antimicrobial Therapy for Difficult-to-treat Pseudomonas Aeruginosa

Pneumococcal Carriage, Serotypes, and Antibiotic Resistance in Malaysian Children: A Multi-Centre Study

FMT for the Decolonization of Carbapenem-resistant Enterobacteriaceae

Infection Risk Associated With Digestive MDRO Carriage in Hospitalized Patients

A Phase 1 Study of the Safety and Tolerability of Single and Multiple Ascending Doses of BWC0977 in Healthy Volunteers

All recent trials (78 shown)

Characterization of the Synergistic Antibacterial Effect of Verapamil on Bacterial Isolates From Cancer Patients

Feasibility of the Application of a New Six-month Treatment for Multidrug-resistant Tuberculosis (MDR-TB) Patients in Fr…

Resistant Bacteria in Children in France

Antimicrobial Resistant Organism Decolonization After Microbiome Perturbation

Modulation of Gut MicroFLORA With Rifaximin to Reduce High Platelet Reactivity in Post-ACS Patients on Ticagrelor

Impact of Three Probabilistic Antibiotic Therapy on Digestive Microbiota and Colonization With Multi-resistant Bacteria

Prospective Study Evaluate the Timing of Empirical Treatment for Carbapenem-resistant Bacterials (CROEAT Study)

Fluoroquinolone Resistance Prevalence Study

Prediction of Multidrug-resistant Bacterial Infection in Patients with Cirrhosis

Antibiotic Prophylaxis in Lung-Transplant Recipients

Evaluation of the Variation of the Intestinal Microbiota and the Integrity of the Intestinal Barrier in Patients With M.…

Use of New Antibiotics in Sweden

Effect of a Bundle of Interventions on the Outcomes of Patients With Intracranial Devices (ICP Monitor e EVD)

Screening of Multidrug Resistant Bacteria, and the Clinical Implication for the Patient

Sentinel Cohort REACT

Distinguishing Bacterial and Viral Infections by MeMed BV® Test to Limit Gut Colonization by MDRO

Multi-drug Resistant Gram-negative Bacteria and Veno-venous Extracorporeal Membrane Oxygenation (ECMO)

Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization

Synergistic Effect of Plasmid Inhibitors and Antimicrobial Drugs Against Clinical MDR-hvKP

Probiotics and Multi-Drug Resistant Urinary Tract Infection