CompletedNot Applicable

Prediction of Multidrug-resistant Bacterial Infection in Patients with Cirrhosis

Argentina1,774 participantsStarted 2022-11-16

Plain-language summary

The aim of this study is to identify predictive factors of infections caused by multidrug-resistant organisms in patients with cirrhosis and to develop and validate (internally and externally) a predictive model that might be useful to use in clinical settings to stratify the risk and lead clinical decision-making strategies.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. age ≥ 18 years
. with cirrhosis
. who presented their first confirmed diagnosis of bacterial infection during the study period, either at admission or during hospitalization

Exclusion criteria

. hepatocellular carcinoma beyond the Milan criteria;
. extrahepatic malignancy;
. severe extrahepatic disease (congestive heart failure \[New York Heart Association stage3\], chronic obstructive pulmonary disease \[Global Initiative for Chronic Obstructive Lung Disease stage 3\]; chronic kidney disease requiring renal replacement therapy \[RRT\]);

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Infection caused by multidrug-resistan organism

Timeframe: 24-48 hours (it is a cross sectional study)

Trial details

NCT IDNCT05641025

SponsorHospital Italiano de Buenos Aires

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-12-30

View on ClinicalTrials.gov More Drug Resistance, Multiple trials