Not Yet RecruitingPhase 1/2
NCT06792500A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, S…
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis,…
United States24 participantsStarted 2026-10Updated 2026-06-04 Treatment: Glycerol Tributyrate
Active — Not RecruitingPhase 2
NCT06402123A Phase 2b Study of Zagociguat in Patients With MELAS
PRIZM is a Phase 2b randomized, double-blind, placebo-controlled, 3-treatment, 2-period, crossover study evaluating the efficacy and safety of oral zagociguat 1…
United States, Australia +4 more43 participantsStarted 2024-09-10Updated 2026-03-25 Treatment: zagociguat 15mg, zagociguat 30mg