Malaria, Antepartum

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Malaria, Antepartum trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

RecruitingNot Applicable

NCT02471378

Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates

Background: \- Malaria is a disease that affects many people in African countries. It is caused by germs that are spread by mosquito bites. It can be fatal if…

Mali7,476 participantsStarted 2015-07-28

RecruitingPhase 3

NCT06962319

Safety of Antimalarials in the FIRst trimEster

The SAFIRE study aims to find effective treatments with acceptable safety for malaria in early pregnancy, a particularly sensitive time for the adverse conseque…

Burkina Faso, Kenya, Mali1,510 participantsStarted 2025-09-30

Treatment: dihydroartemisinin-piperaquine (DP), Pyronaridine-artesunate (PA)

RecruitingNot Applicable

NCT06529237

Malaria Molecular Surveillance in Mozambique (Phase 2)

Mozambique is among the ten countries with the highest burden of malaria worldwide, with an estimated 10.3 million cases in 2021. Malaria transmission is highly…

Mozambique18,750 participantsStarted 2024-04-01

Treatment: LDH-based malaria rapid diagnostic test, Malaria rapid diagnostic test

All recent trials (64 shown)

Active — Not RecruitingPhase 4

NCT05757167

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics

The purpose of the INTREPiD study is to compare 1st trimester screening for malaria parasites with a high-sensitivity malaria rapid diagnostic test followed by…

Democratic Republic of the Congo, Kenya2,174 participantsStarted 2023-11-06

Treatment: Malaria High-Sensitivity Rapid Diagnostic Test (HS-RDT), Artemether-lumefantrine (AL)

Not Yet RecruitingEarly Phase 1

NCT07021430

Focal Mass Drug Administration for the Prevention of Malaria in Pregnancy

The purpose of this study is to demonstrate the feasibility, acceptability, and preliminary effectiveness of a focal mass drug administration program for househ…

Uganda300 participantsStarted 2026-04

Treatment: Dihydroartemisinin Piperaquine

Malaria, Antepartum

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates

Safety of Antimalarials in the FIRst trimEster

Malaria Molecular Surveillance in Mozambique (Phase 2)

All recent trials (64 shown)

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics

Focal Mass Drug Administration for the Prevention of Malaria in Pregnancy

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates

Safety of Antimalarials in the FIRst trimEster

Malaria Molecular Surveillance in Mozambique (Phase 2)

All recent trials (64 shown)

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics

Focal Mass Drug Administration for the Prevention of Malaria in Pregnancy

Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy

Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women

LAMP Detection of Malaria in PREGnancy (LAMPREG) Trial

Plasmodium Falciparum Genomic Intelligence in Mozambique

Follow-up of Immunological Pattern and Pregnancy Outcomes in Women Previously Received Placental Malaria Vaccine

Intermittent Preventive Treatment With Dihydroartemisinin-piperaquine in Papua, Indonesia

Clinical Performance of the HRP2 HS-RDT for Malaria Diagnosis in Pregnant Women

A Novel Regimen to Prevent Malaria and STI in Pregnant Women With HIV

TIPTOP Sulfadoxine-pyrimethamine (SP) Drug Resistance Study

The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract

Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG)

Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa

Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During Pregnancy

ERASE - Impact of COVID-19 on Malaria Control

Evaluating the Effects of Community Delivery of Malaria Intermittent Preventive Treatment on Pregnant Women and Babies

Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in Pregnancy

Assessing the Impact of Group Antenatal Care on IPTp Uptake in Tanzania

Assessing the Effectiveness of Community Delivery of Intermittent Preventive Treatment in Pregnancy (IPTp) in Malawi