Macular Telangiectasia Type 2 (MacTel)

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Macular Telangiectasia Type 2 (MacTel) trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 4

NCT06971939

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

The purpose of this global, multicenter, open-label, Phase 4 clinical extension study is to evaluate the long-term safety and efficacy of revakinagene taroretce…

United States285 participantsStarted 2025-11-21

Treatment: NT-501/revakinagene taroretcel-lwey

All recent trials (13 shown)

Not Yet RecruitingPhase 3

NCT07342439

Study of Serine Supplementation to Protect Vision in MacTel

The goal of this clinical trial is to look at the efficacy and safety of giving oral serine (an amino acid) on the progression of structural and functional chan…

United States, Australia120 participantsStarted 2026-09

Treatment: L-serine, Placebo

Active — Not RecruitingPhase 3

NCT06397131

A Study to Determine the Safety and Efficacy of NT-501 With MHFM

This study is to determine the long-term levels of CNTF, and the clinical safety and efficacy of the NT-501 implants with the Medica Hollow Fiber Membrane (MHFM…

United States12 participantsStarted 2025-03-06

Treatment: NT-501 CNTF Implant

Macular Telangiectasia Type 2 (MacTel)

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

All recent trials (13 shown)

Study of Serine Supplementation to Protect Vision in MacTel

A Study to Determine the Safety and Efficacy of NT-501 With MHFM

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

All recent trials (13 shown)

Study of Serine Supplementation to Protect Vision in MacTel

A Study to Determine the Safety and Efficacy of NT-501 With MHFM

Extension Study of NT-501 Ciliary Neurotrophic Factor (CNTF) Implant for Macular Telangiectasia (MacTel)

Safety Study to Evaluate Bilateral CNTF Implants in Subjects With MacTel Type 2

A Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2 - Protocol A

A Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2 - Protocol B

Serine and Fenofibrate Study in Patients With MacTel Type 2

MacTel Laser Study

A Study to Evaluate THR-317 Treatment for Macular Telangiectasia Type 1 (MacTel 1)

A Phase 2 Multicenter Randomized Clinical Trial of CNTF for MacTel

The Role of Macular Pigment Carotenoids in the Pathogenesis and Treatment of Macular Telangiectasia Type 2 (MacTel)

Ciliary Neurotrophic Factor (CNTF) Safety Trial in Patients With Macular Telangiectasia (Mactel)