This was a prospective, multicenter, single-masked, sham-controlled extension study designed to provide long-term safety and efficacy follow-up data for subjects with MacTel who had NT-501 implanted intraocularly and/or underwent sham surgery in the respective precursor study (NTMT-01 or NTMT-02). A substudy was conducted in which subjects enrolled in study (NTMT-02), who had 1 study-eligible eye that underwent sham surgery, were offered the option to have NT-501 implanted in the same study eye. Of the 19 subjects who had 1 study-eligible eye and underwent sham surgery in the Cohort 2 precursor study (NTMT-02), 16 subjects elected to have NT-501 implanted in the same study eye during the substudy
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Ellipsoid Zone (Area of IS/OS Loss) - Cohort 1
Timeframe: 72, 84, 96, and 108 months (based on participants' original implant date during precursor study)
Ellipsoid Zone (Area of IS/OS Loss) - Cohort 2
Timeframe: Baseline to 36, 48, 60 and 72 Months post-surgery (based on participants' original implant date during precursor study)