Low Grade Ovarian Serous Adenocarcinoma

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Low Grade Ovarian Serous Adenocarcinoma trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingPhase 1

NCT05950464

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endo…

This phase Ib trial tests the safety, side effects, and best dose of M1774 when given with ZEN-3694 in treating patients with ovarian and endometrial cancer tha…

United States65 participantsStarted 2023-12-18

Treatment: BET Bromodomain Inhibitor ZEN-3694, Biopsy Procedure

RecruitingPhase 2

NCT06494150

Nab-Sirolimus and Endocrine Therapy in Recurrent Low Grade Serous Ovarian Cancer (NARETO)

This single arm phase II study proposes to evaluate the efficacy and safety of nab-sirolimus + endocrine therapy (Fulvestrant) in patients with recurrent low gr…

United States37 participantsStarted 2024-12-26

Treatment: nab-Sirolimus, Fulvestrant

RecruitingNot Applicable

NCT00488878

Data Collection for Patients With Low Grade Ovarian or Peritoneal Tumors

This study collects information to maintain a database on patients with low-grade ovarian or peritoneal tumors. Collecting information about the type of cancer…

United States2,000 participantsStarted 2006-05-19

Treatment: Biospecimen Collection, Electronic Health Record Review

RecruitingPhase 3

NCT05601700

Letrozole for Estrogen/Progesterone Receptor Positive Low-grade Serous Epithelial Ovarian Cancer (LEPRE Trial)

This is an Italian, multicenter, randomized, open-label phase III trial which will evaluate if Letrozole is superior to standard adjuvant chemotherapy in patien…

Italy132 participantsStarted 2022-09-22

Treatment: Letrozole tablets, carboplatin AUC 5 and paclitaxel 175 mg/m2

All recent trials (16 shown)

Active — Not RecruitingPhase 2

NCT02834013

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipil…

United States818 participantsStarted 2017-01-30

Treatment: Biospecimen Collection, Computed Tomography

Active — Not RecruitingPhase 2

NCT05554367

Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial

This phase II ComboMATCH treatment trial evaluates the effectiveness of palbociclib and binimetinib in treating patients with RAS-mutated cancers. Palbociclib a…

United States199 participantsStarted 2023-12-13

Treatment: Binimetinib, Biopsy Procedure

Low Grade Ovarian Serous Adenocarcinoma

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endo…

Nab-Sirolimus and Endocrine Therapy in Recurrent Low Grade Serous Ovarian Cancer (NARETO)

Data Collection for Patients With Low Grade Ovarian or Peritoneal Tumors

Letrozole for Estrogen/Progesterone Receptor Positive Low-grade Serous Epithelial Ovarian Cancer (LEPRE Trial)

All recent trials (16 shown)

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endo…

Nab-Sirolimus and Endocrine Therapy in Recurrent Low Grade Serous Ovarian Cancer (NARETO)

Data Collection for Patients With Low Grade Ovarian or Peritoneal Tumors

Letrozole for Estrogen/Progesterone Receptor Positive Low-grade Serous Epithelial Ovarian Cancer (LEPRE Trial)

All recent trials (16 shown)

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansi…

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or P…

Phase I Trial of Defactinib and VS-6766.

Fulvestrant Plus Abemaciclib in Women With Advanced Low Grade Serous Carcinoma

Ribociclib and Letrozole Treatment in Ovarian Cancer

Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer

Study of Pembrolizumab Combination With Chemotherapy in Platinum-sensitive Recurrent Low-grade Serous Ovarian Cancer

A Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer Wi…

Selumetinib Sulfate in Treating Woman With Recurrent Low-Grade Ovarian Cancer or Peritoneum Cancer