This phase II trial studies the side effects and how well selumetinib sulfate works in treating patients with low-grade ovarian cancer that has come back (recurrent). Selumetinib sulfate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
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Tumor Response
Timeframe: Every other cycle
Adverse Events (Grade 3 or Higher) During First Cycle of Treatment
Timeframe: Cycle 1
Area Under the Curve (AUC) for AZD6244, 100 mg Administered Orally Twice Daily.
Timeframe: Pre-dose, and 1, 3, and 6 hours after administration of drug on Day 7 after the start of AZD6244 treatment
Maximum Concentration (Cmax) for AZD6244, 100 mg Administered Orally Twice Daily.
Timeframe: Pre-dose, and 1, 3, and 6 hours after administration of drug on Day 7 after the start of AZD6244 treatment