Locally Advanced Leiomyosarcoma

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Locally Advanced Leiomyosarcoma trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 2

NCT04383119

Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma

Study is aimed at evaluating the activity of Trabectedin (arm A) in advanced leiomyosarcomas, having Gemcitabine (arm B) as the comparator. In addition to the…

Italy100 participantsStarted 2021-10-29

Treatment: Trabectedin, Gemcitabine

All recent trials (20 shown)

Active — Not RecruitingPhase 2

NCT05836571

Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft T…

This phase II trial compares the effect of immunotherapy with ipilimumab and nivolumab alone to their combination with cabozantinib in treating patients with so…

United States66 participantsStarted 2023-10-25

Treatment: Biopsy Procedure, Biospecimen Collection

Active — Not RecruitingPhase 2/3

NCT05432791

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped W…

This phase II/III trial compares the effect of the combination treatment with olaparib and temozolomide to trabectedin or pazopanib (two of the most common chem…

United States74 participantsStarted 2023-03-30

Treatment: Biospecimen Collection, Bone Scan

Locally Advanced Leiomyosarcoma

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma

All recent trials (20 shown)

Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft T…

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped W…

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma

All recent trials (20 shown)

Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft T…

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped W…

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With…

A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS)

A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Niraparib for the Treatment of Leiomyosarcoma

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed…

Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma

Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma

A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma

AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma

Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft T…

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma

Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft T…

A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Canc…

Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma

Temozolomide and Thalidomide in Treating Patients With Metastatic, Locally Advanced, or Unresectable Leiomyosarcoma

Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma