Internal Carotid Stenosis

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Internal Carotid Stenosis trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

RecruitingNot Applicable

NCT07462546

Transcranial Doppler for Internal Carotid Artery Stenting (TCD-ICAS)

Carotid artery stenting (CAS) prevents stroke but carries risks of perioperative cerebral embolism. Transcranial Doppler (TCD) ultrasound can detect microemboli…

China232 participantsStarted 2026-03-24

Treatment: Transcranial Doppler

RecruitingPhase 2/3

NCT07282041

Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis

One important mechanism of action of GLP1 RA is the improvement in endothelial function, which may be evaluated by the assessment of cerebral vasodilatory reser…

Singapore130 participantsStarted 2025-12-17

Treatment: Dulaglutide

RecruitingPhase 2

NCT07104487

[18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease

This clinical trial aims to evaluate whether \[¹⁸F\]AlF-OC PET/MRI can characterize and quantify inflammation in carotid atherosclerotic plaques. The study will…

Belgium24 participantsStarted 2025-03-18

Treatment: [18F]AlF-OC

RecruitingNot Applicable

NCT01793168

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, i…

United States, Australia20,000 participantsStarted 2010-07

RecruitingNot Applicable

NCT04261478

Endovascular Acute Stroke Intervention - Tandem OCclusion Trial

Patients with tandem occlusion or tandem lesion (TL), that is, stroke with an acute intracranial anterior circulation occlusion and an ipsilateral cervical ICA…

Canada458 participantsStarted 2020-08-31

Treatment: Carotid artery stenting, Antiplatelet Agents

All recent trials (27 shown)

CompletedNot Applicable

NCT03921827

External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis

Intracranial stenosis is prevalent among Asians and constitute a common cause of cerebral ischemia. While the best medical therapy carries stroke recurrence rat…

Singapore130 participantsStarted 2019-01-08

Treatment: Enhance External Counterpulsation Therapy

Active — Not RecruitingPhase 3

NCT03121209

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H)

We aim to determine whether cognitive impairment attributable to cerebral hemodynamic impairment in patients with high-grade asymptomatic carotid artery stenosi…

United States385 participantsStarted 2018-01-18

Treatment: Revascularization, Intensive Medical Management (IMM) alone

Internal Carotid Stenosis

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Transcranial Doppler for Internal Carotid Artery Stenting (TCD-ICAS)

Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis

[18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Endovascular Acute Stroke Intervention - Tandem OCclusion Trial

All recent trials (27 shown)

External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H)

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Transcranial Doppler for Internal Carotid Artery Stenting (TCD-ICAS)

Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis

[18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Endovascular Acute Stroke Intervention - Tandem OCclusion Trial

All recent trials (27 shown)

External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H)

Assessment of Vulnerability to Carotid Stenosis by MultiModal Imaging and Cellular and Molecular Biology Analysis

Ultrafast Ultrasound Imaging Assesment of Carotid Plaque Neovascularization

Innovative Application of Pressure Gradient Measurement in Internal Carotid Stenosis in Patients Undergoing CAS

Medico-economic Evaluation of Preoperative Cerebral Oximetry Monitoring During Carotid Endarterectomy

SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy

A Study of Evolocumab on Carotid Artery Atherosclerotic Plaque Morphology Prior to Carotid EndArterectomy

Advanced Ultrasound Methods in the Assessment of Carotid Plaque Instability

The Observation About the Effects of Internal Carotid Artery Stenosis on Fundus Vessels and the Changes of Fundus Vessel…

A Perspective, Self-control Study on the Progression of Carotid Plaques in Anti-PD-1 mAb Treated Tumor Patients by Arter…

99mTc-rhAnnexin V-128 Imaging for Carotid Atherosclerosis

Long-term Follow-up NIRS-IVUS Imaging of Pre-existing Carotid Stents

Ultrasound-guided Intermediate Cervical Plexus Block

Pilot Study of Autoarterial Remodeling of Bifurcation of the Common Carotid Artery

SONOlysis in Prevention of Brain Infarctions dUring Carotid Stenting and caroTid EndaRterectomy

Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis

MICHI™ Neuroprotection System (NPS+f) Filter Debris Analysis Study (The F-1 Study)

A Prospective, Non-Randomized, Evaluation of Low-Risk Patients Undergoing Carotid Stenting With ANgiomax (Bivalirudin)

Early Warning and Optimization Strategy in Carotid Endarterectomy