UnknownPhase 4

Early Warning and Optimization Strategy in Carotid Endarterectomy

China150 participantsStarted 2010-01

Plain-language summary

Carotid endarterectomy has been proven effective in prevention of cerebral vascular events in patients with severe carotid artery stenosis (symptomatic,\>50%;asymptomatic,60%). But during the surgery, when the carotid artery is clipping, the patient will have the chance to have hypoperfusion or stroke. Our study is designed to determine how to use TCD to reduce the risk of death and nonfatal stroke in patients .

Who can participate

Age range40 Months – 80 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Carotid artery stenosis detectable by duplex ultrasound, and no previous procedure done on it, which might well need procedural treatment now with CEA or CAS. * Already started any appropriate medical treatment (eg, statin, aspirin etc), and already recovered from any necessary coronary procedures (eg, CABG) * Patient seems fit and willing for follow-up in person (at 1 month) and by annual letter (for at least 5 years) * Some type of angiography (eg, MRA or CTA) has already been done that has shown that CEA . Exclusion Criteria: * Small likelihood of worthwhile benefit (eg, very low risk of stroke because stenosis is very minor, or major co-morbidity or life-threatening disease, such as advanced cancer)

What they're measuring

Mortality

Timeframe: 30 days

Trial details

NCT IDNCT01210937

SponsorPeking Union Medical College Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-12

View on ClinicalTrials.gov More Carotid Stenosis trials