İntensive Care

Clinical trial pipeline · Data from ClinicalTrials.gov

See which İntensive Care trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

RecruitingPhase 3

NCT05075161

Pirfenidone to Prevent Fibrosis in Ards.

Acute respiratory distress syndrome (ARDS) is a severe form of acute lung injury and a major cause of Intensive Care Unit (ICU) admission worldwide. Despite a l…

Italy130 participantsStarted 2022-06-01

Treatment: Pirfenidone, Placebo

RecruitingNot Applicable

NCT05928767

Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted…

The aim of the study is to demonstrate that "frail" patients, defined as having a CFS score greater than or equal to 5, and "severely" frail patients, defined a…

France200 participantsStarted 2023-08-21

RecruitingNot Applicable

NCT07032987

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Sedation (painkillers and sedative drugs) treats pain, reduces suffering, and helps patients in the intensive care unit (ICU) receiving extracorporeal membrane…

United Kingdom120 participantsStarted 2025-11-24

Treatment: Not an intervention study

RecruitingNot Applicable

NCT05936710

Improved Hemodynamic Tolerance of Intermittent Hemodialysis Sessions in Intensive Care Unite Using Citrate- vs Acetate-b…

During intermittent hemodialysis (IHD), the occurrence of intradialytic hemodynamic instability (IHI) is frequent in ICU and impacted morbidity and mortality. B…

France48 participantsStarted 2023-12-07

Treatment: ACETATE based dialysate, CITRATE based dialysate

RecruitingNot Applicable

NCT07300306

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

The goal of this observational study is to validate the effectiveness of the new SOFA-2 score in predicting mortality and to determine the current frequency of…

Turkey (Türkiye)2,500 participantsStarted 2026-05-04

RecruitingNot Applicable

NCT07538102

Respiratory Physiotherapy and Diaphragm Thickness in Ventilated ICU Patients

This study aims to evaluate the effect of respiratory physiotherapy on diaphragm thickness in patients receiving mechanical ventilation support in the intensive…

Turkey (Türkiye)66 participantsStarted 2025-08-01

Treatment: Standard ICU Physiotherapy, Neuromuscular Electrical Stimulation (NMES)

All recent trials (100 shown)

Active — Not RecruitingPhase 2

NCT05996835

Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (CLEAR-AKI)

The purpose of this Ph2b study is to characterize the dose-response relationship and to evaluate the safety and efficacy of three different single doses of TIN8…

United States320 participantsStarted 2024-01-18

Treatment: TIN816 70 mg lyophilisate powder, Placebo

Active — Not RecruitingNot Applicable

NCT04956354

The Use of Wireless Sensors in Neonatal Intensive Care

The study will be conducted in a convenience sample of 75 infants admitted to the NICU at the Montreal Children's Hospital, divided into 3 phases: (a) Phase 1a…

Canada75 participantsStarted 2022-08-15

Treatment: ANNE™ Monitoring System (2 sensors) - version B, ANNE™ Monitoring System (2 sensors) - version C

İntensive Care

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

Pirfenidone to Prevent Fibrosis in Ards.

Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted…

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Improved Hemodynamic Tolerance of Intermittent Hemodialysis Sessions in Intensive Care Unite Using Citrate- vs Acetate-b…

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

Respiratory Physiotherapy and Diaphragm Thickness in Ventilated ICU Patients

All recent trials (100 shown)

Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (CLEAR-AKI)

The Use of Wireless Sensors in Neonatal Intensive Care

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

Pirfenidone to Prevent Fibrosis in Ards.

Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted…

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Improved Hemodynamic Tolerance of Intermittent Hemodialysis Sessions in Intensive Care Unite Using Citrate- vs Acetate-b…

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

Respiratory Physiotherapy and Diaphragm Thickness in Ventilated ICU Patients

All recent trials (100 shown)

Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (CLEAR-AKI)

The Use of Wireless Sensors in Neonatal Intensive Care

Psychometric Evaluation of the EVARUCI Scale in Turkish Intensive Care Units

Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections

Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or…

Nurses' Knowledge, Attitudes, and Behaviours Related to Eye Care in the ICU

Whole-Body Vibration Versus Neuro Muscular Electrical Stimulation on Patients With ICU Acquired Weakness

Effect of Bed Bathing Methods on VRE Colonization in ICU Patients

Combined Predictive Value of RSBI and CALLY Index in Predicting Weaning Success in ICU Patients

Oscillometric Blood Pressure Measurement: Evaluation of the Effect of Wearing a Sleeve and the Type of Measurement Algor…

Pre-ICU Hospital Length of Stay and 30-day Mortality in the Very Old: a National Cohort of 315 042 ICU Admissions

Efficacy of the Alpha 2 Agonist Dexmedetomidine for Sympathetic Deactivation in REfractory Septic Shock

Augmented Pacing for Shock in the Cardiac Intensive Care Unit

Self-hangIng Patient and Hyperbaric Oxygen Therapy _ SIPHON Study

Use of Oxiris Filter in Septic Shock Patients Requiring Renal Replacement Therapy: A Retrospective Cohort Study

PROSpect: Prone and Oscillation Pediatric Clinical Trial

Anemia and Duration of Mechanical Ventilation

A Study to Evaluate the Introduction of New Staffing Models in Intensive Care: a Realist Evaluation (SEISMIC-R)

Clinical Practices of Extubation After Invasive Mechanical Ventilation

TRacheostomy in DElphi for iNTensive Care' (TRiDENT)