RecruitingNot Applicable

Assessment of Reintubation Risk Using Multiple Parameters in Postoperative Intensive Care Unit Patients

Turkey (Türkiye)600 participantsStarted 2026-04-28

Plain-language summary

This prospective, non-interventional observational study will evaluate the risk of reintubation in adult postoperative patients admitted to the intensive care unit after major surgery. Reintubation after extubation is an important clinical problem because it may increase complications, prolong mechanical ventilation, and extend intensive care and hospital stay. The study will include adult patients who are extubated in the operating room and admitted to the intensive care unit with spontaneous breathing. Within the first hours after ICU admission, bedside ultrasound measurements of diaphragm thickness, parasternal intercostal muscle thickness, and lung ultrasound score will be performed. The ROX index will also be calculated using oxygen saturation, inspired oxygen concentration, and respiratory rate. Perioperative fluid balance will be recorded from anesthesia and patient files. Patients will be followed for 48 to 72 hours after ICU admission to determine whether reintubation is required. The study aims to assess whether respiratory muscle ultrasound findings, lung ultrasound score, ROX index, and perioperative fluid balance can help predict reintubation risk in postoperative ICU patients. No additional treatment or intervention will be applied as part of the study, and all clinical decisions will be made by the responsible intensive care team according to routine clinical practice.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Adult patients aged 18 years and older Patients requiring postoperative intensive care follow-up after major surgery, including abdominal, vascular, orthopedic, or ear, nose, throat, head and neck surgery Patients extubated in the operating room and admitted to the intensive care unit with spontaneous breathing Patients without any clinical condition preventing the planned measurements within the first 0-2 hours after ICU admission (T0 and T1) Patients for whom written informed consent can be obtained from the patient or legally authorized representative Patients admitted to the intensive care unit within the specified study period after ethics committee approval and enrolled consecutively Exclusion Criteria: Patients younger than 18 years of age Patients who leave the operating room intubated or are admitted to the intensive care unit while intubated Patients with a tracheostomy Patients with a history of diaphragmatic paralysis Patients with a significant neuromuscular disease, such as ALS, myasthenia gravis, or similar conditions Patients with conditions that significantly prevent ultrasound measurements, including marked subcutaneous emphysema, large dressings or bandages covering the measurement area, inability to access the measurement site due to drains or the surgical field, or inability to obtain technically adequate images Patients in whom the planned measurements cannot be performed due to clinical instability requiring emergency i…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Reintubation Within 72 Hours After Intensive Care Unit Admission

Timeframe: From intensive care unit admission to 72 hours after admission

Trial details

NCT IDNCT07672106

SponsorProf. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-10-28

View on ClinicalTrials.gov More Postoperative Respiratory Failure trials