Hyperlipoproteinemia Type III

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Hyperlipoproteinemia Type III trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingPhase 3

NCT07473960

IBI306 Monotherapy in Non-Familial Hypercholesterolemia and Mixed Hyperlipidemia

This is a multi-center, randomized, double-blind, placebo-controlled phase III clinical study evaluating the efficacy and safety of IBI306 monotherapy in Chines…

China198 participantsStarted 2026-04-01

Treatment: IBI306, placebo

RecruitingPhase 2

NCT07392723

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blo…

United States20 participantsStarted 2025-01-12

Treatment: Alpha-Linolenic Acid (2.6 g/day), Placebo Control Group

RecruitingNot Applicable

NCT04815005

HoFH, the International Clinical Collaborators Registry

Homozygous familial hypercholesterolemia (HoFH), a rare inherited disorder caused by bi-allelic mutations in the LDL Receptor pathway, is characterized by extre…

United States, Netherlands, South Africa1,000 participantsStarted 2017-01-24

Treatment: Demographics, diagnosis type, genotype, lipid profile, treatment allocation, country of residence.

RecruitingNot Applicable

NCT06535542

Integrating Whole Genome Sequencing and Digital Twins Into the Management of Hypercholesterolemia in Emiratis

This pilot study investigates integrating whole genome sequencing and digital twin technology for managing hypercholesterolemia in Abu Dhabi clinics. It aims to…

United Arab Emirates40 participantsStarted 2024-07-29

Treatment: Whole Genome Sequencing

All recent trials (27 shown)

CompletedNot Applicable

NCT00001168

Evaluation of Lipoproteins

Lipoproteins are particles that carry fats such as cholesterol and triglycerides through the blood stream. These particles are involved in causing blood vessel…

United States1,017 participantsStarted 1979-01-01

Treatment: Balanced diet

CompletedNot Applicable

NCT05218005

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

ACCURATE will test the hypothesis that opportunistic genetic testing for Familial Hypercholesterolemia (FH) in patients admitted to hospital with an acute coron…

Canada140 participantsStarted 2022-01-01

Treatment: Research-based genetic test for Familial Hypercholesterolemia

Hyperlipoproteinemia Type III

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

IBI306 Monotherapy in Non-Familial Hypercholesterolemia and Mixed Hyperlipidemia

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

HoFH, the International Clinical Collaborators Registry

Integrating Whole Genome Sequencing and Digital Twins Into the Management of Hypercholesterolemia in Emiratis

All recent trials (27 shown)

Evaluation of Lipoproteins

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

IBI306 Monotherapy in Non-Familial Hypercholesterolemia and Mixed Hyperlipidemia

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

HoFH, the International Clinical Collaborators Registry

Integrating Whole Genome Sequencing and Digital Twins Into the Management of Hypercholesterolemia in Emiratis

All recent trials (27 shown)

Evaluation of Lipoproteins

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

QLC7401 in the Treatment of Primary Hypercholesterolemia or Mixed Hyperlipidemia With Elevated Low Density Lipoprotein C…

QLC7401 Monotherapy in Non-familial Hypercholesterolemia or Mixed Dyslipidemia

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety…

Compassionate Use of Evinacumab

Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

Genetic Testing and Motivational Counseling for FH

A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholeste…

Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (…

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia

Study of SHR-1209 in the Treatment of Hypercholesterolemia and Hyperlipidemia Ⅲ Stage

Evaluate the Efficacy and Safety of IBI306 in Subjects With Homozygous Familial Hypercholesterolemia

Effects of Evolocumab Versus Placebo Added to Standard Lipid-lowering Therapy on Fasting and Post Fat Load Lipids in Pat…

Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia

A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)

Perioperative Research Into Memory, Genomics in the Intensive Therapy Unit: Alzheimer's

DARK STUDY "DysbetalipoproteinemiA and atheRoma Risk"

Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Subjects With A Genetic Cholesterol Disorder.