The main aim of this study is to understand how moderate and severe liver impairment (based on the Child-Pugh classification) affects the body's processing of a…

United States31 participantsStarted 2025-03-14

Treatment: Palovarotene, Palovarotene

Not Yet RecruitingPhase 1

NCT07551557

Pharmacokinetics of VC005 Tablets in Subjects With Hepatic Impairment and Normal Hepatic Function

This study is a Phase I, single-dose, open-label trial designed to evaluate the pharmacokinetics and safety of a single oral dose of 25 mg VC005 tablets in part…

China24 participantsStarted 2026-04-30

Treatment: VC005 Tablets

Hepatic Impairment and Healthy Female

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepati…

All recent trials (26 shown)

A Study of the Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Parti…

Pharmacokinetics of VC005 Tablets in Subjects With Hepatic Impairment and Normal Hepatic Function

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepati…

All recent trials (26 shown)

A Study of the Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Parti…

Pharmacokinetics of VC005 Tablets in Subjects With Hepatic Impairment and Normal Hepatic Function

GS1-144 in Participants With Hepatic Impairment and Healthy Female

A Study of Camlipixant in Male and Female Healthy Participants and Participants With Hepatic Impairment Aged 18-75 Years…

A Study to Test How Zongertinib is Taken up in the Blood of People With and Without Liver Problems

A Study of Effects of Selpercatinib in Hepatically Impaired Participants and Healthy Participants

Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment

Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Liver Function and Healthy Participants

GP681 in Volunteers With Hepatic Impairment Compared With Healthy Volunteers

A Study to Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment

A Study to Learn How Finerenone (BAY94-8862) Moves Into, Through and Out of the Body, How it Affects the Body, and How S…

Study of Copanlisib in Hepatic or Renal Impairment

Effect of Hepatic Impairment on LDE225..

Study on the Safety of BAY 63-2521, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the St…

Safety and Pharmacokinetics Study of Linzagolix in Female Subjects With Normal and Impaired Hepatic Function

A Safety Study of Tucatinib in Healthy and Hepatically-Impaired Subjects

Study to Evaluate a Dose of Telotristat Etiprate in Male and Female With Mild, Moderate and Severe Hepatic Insufficiency…

Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding

PK Study of Sotagliflozin in Subjects With Hepatic Impairment

Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy Volunteers