BAY 63-2521 is intended to be used for a disease that affects the blood flow through the lungs. Renal impairment is a common condition in patients with this disease. The goal of the study is to learn more about the safety of BAY 63-2521, how it is tolerated and the way the body absorbs, distributes and gets rid of the study dug given as a single oral dose of 1 mg tablet in participants with renal impairment and healthy participants matched for age-, gender-, and weight
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AUC
Timeframe: Pre-dose and up to 72 hours post-dose, additionally up to 96 hours post-dose for Child Pugh B group only
Cmax
Timeframe: Pre-dose and up to 72 hours post-dose, additionally up to 96 hours post-dose for Child Pugh B group only
t½
Timeframe: Pre-dose and up to 72 hours post-dose, additionally up to 96 hours post-dose for Child Pugh B group only
fu
Timeframe: From 2 hours post-dose up to 24 hours post-dose
AUCu
Timeframe: From 2 hours post-dose up to 24 hours post-dose
Cmax,u
Timeframe: From 2 hours post-dose up to 24 hours post-dose