Fluoroquinolone

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Fluoroquinolone trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingPhase 3

NCT07209761

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

This study aims to assess quabodepistat-based treatment regimens for RR/MDR-TB. The study will enroll adults and adolescents with rifampicin-resistant or multid…

China532 participantsStarted 2025-10-16

Treatment: BPaQM, BPaLM

RecruitingPhase 4

NCT05199324

Early Oral Switch for Uncomplicated Gram-negative Bacteraemia

Current management of uncomplicated Gram-negative bacteraemia entails prolong intravenous (IV) antibiotic therapy with limited evidence to guide oral conversion…

Singapore720 participantsStarted 2022-06-03

Treatment: Oral fluoroquinolones (most commonly, ciprofloxacin) or oral trimethoprim-sulfamethoxazole, Standard of care intravenous antibiotics (e.g. ceftriaxone, cefazolin)

RecruitingNot Applicable

NCT02539407

Population Pharmacokinetics of Anti-infectives in Critically Ill Children

Concentrations and effects of anti-infectives in critically ill children are unpredictable and the risk of under-exposure may be associated with poor clinical o…

France3,000 participantsStarted 2015-09-11

Treatment: Pharmacokinetics

RecruitingPhase 1/2

NCT06938867

Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administ…

This is a Phase 1b/2a study in allogenic hematopoietic stem cell transplant patients to investigate the safety, PK, PD and preliminary efficacy of multiple oral…

United States24 participantsStarted 2025-02-25

Treatment: SNIPR001 consists of genetically modified bacteriophages specifically targeting Escherichia coli, Placebo 10 mL

All recent trials (65 shown)

Not Yet RecruitingNot Applicable

NCT07559318

Post-Emergency Optimization of Antibiotic Therapy for Urinary Tract Infection (UTI)

Prospective, multicenter, non-interventional study conducted over 6 months, including patients presenting to the emergency department with suspected urinary tra…

Location not specified330 participantsStarted 2026-06-01

Treatment: Adaptation of antibiotics therapy for outpatient urinary infection following emergency care

Active — Not RecruitingNot Applicable

NCT05117788

Bioneer Q-RFIA Clinical Evaluation

Robust evidence on the clinical diagnostic accuracy and operational characteristics of the Bioneer Accupower Q-RFIA PCR kit on IRON qPCR is required to comprehe…

Kenya, Moldova +3 more2,350 participantsStarted 2022-02-23

Treatment: Estimate the diagnostic accuracy of the Bioneer Accupower Q-RFIA PCR kit on IRON qPCR for MTB detection using culture as reference standard. Estimate the diagnostic accuracy of the Bioneer Ac

Fluoroquinolone

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

Early Oral Switch for Uncomplicated Gram-negative Bacteraemia

Population Pharmacokinetics of Anti-infectives in Critically Ill Children

Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administ…

All recent trials (65 shown)

Post-Emergency Optimization of Antibiotic Therapy for Urinary Tract Infection (UTI)

Bioneer Q-RFIA Clinical Evaluation

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

Early Oral Switch for Uncomplicated Gram-negative Bacteraemia

Population Pharmacokinetics of Anti-infectives in Critically Ill Children

Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administ…

All recent trials (65 shown)

Post-Emergency Optimization of Antibiotic Therapy for Urinary Tract Infection (UTI)

Bioneer Q-RFIA Clinical Evaluation

A Sticker Reminder Intervention to Promote IV-to-PO Fluoroquinolone Switching

Testing New Strategies for Patients Hospitalised With HIV-associated Disseminated Tuberculosis

A Study of Fluoroquinolones Exposure and Collagen-Related Serious Adverse Events

Fluoroquinolone Resistance Prevalence Study

Comparison Between Levofloxacin and Prulifloxacin, in Internal Medicine Patients With Acute Exacerbation of COPD

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endT…

Clinical Study on the Early Bactericidal Activity of Sitafloxacin Against Mycobacterium Abscessus Disease

FQ Restriction for the Prevention of CDI

Treatment Shortening of MDR-TB Using Existing and New Drugs

Registry on the Effectiveness and Safety of the 9-month MDR-END Treatment Regimen in Korean Patients with FQ-sensitive M…

TB-CAPT MTB/XDR Study

Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of…

Antibiotic Treatment for 7 Days Versus 14 Days in Patients With Acute Male Urinary Tract Infection

Therapeutic Drug Monitoring in Patients With Difficult-to-Treat Gram-Negative Bacterial Infections

Development of an Adjustment Assistance Tool Dosage of Fluoroquinolones in a Population Pharmacokinetic Model

Quinolone Resistance Profiles and Mechanisms of Staphylococcus Aureus and Escherichia Coli From Humans, Chicken and Catf…

Bioequivalence Study of Mofest® 400mg (Moxifloxacin) Tablet With Avelox® 400mg (Moxifloxacin) Tablet in Healthy Pakistan…

Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic Malignancies