Fluid Challenge

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Fluid Challenge trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 11 trials

RecruitingPhase 4

NCT05726136

Fluid Challenge and Plasma Volume, During Surgery

A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the…

Sweden60 participantsStarted 2023-10-23

Treatment: acetated Ringers, albumin 5%

RecruitingNot Applicable

NCT06486467

Reliability of Minimally Trained Operator's Velocity-Time Integral Measurement Guided by Artificial Intelligence VTI

Stroke volume is a major determinant of tissue perfusion and therefore a key parameter to monitor in patients with hemodynamic instability and hypoperfusion. Le…

France100 participantsStarted 2024-11-14

Treatment: Fluid challenge (cristalloids) OR passive leg raising

RecruitingNot Applicable

NCT07039773

Gluten Challenge in Celiac Disease - Which Formulation of Gluten Gives the Best Response?

The goal of this clinical trial is to evaluate the immune response to gluten in patients with celiac disease (CeD) by comparing different forms of gluten admini…

Norway30 participantsStarted 2025-08-01

Treatment: Vital wheat gluten, Vital wheat gluten

RecruitingNot Applicable

NCT07202637

Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness

Fluid administration is the first-line treatment in hypovolemic states in critically ill patients. Prediction of fluid responsiveness is possible with echocardi…

France205 participantsStarted 2024-11-07

Treatment: Fluid bolus administration

RecruitingNot Applicable

NCT06384287

Peripheral Tissue Perfusion in Intensive Care

Tissue perfusion has been identified as an early prognosis factor in patients admitted to intensive care. However, little is known about the effects of differen…

France180 participantsStarted 2024-06-22

RecruitingNot Applicable

NCT07030010

Effect of a Liquid Tonic Drink on Post-meal Glucose and Insulin Responses

A randomised, double blinded, placebo-controlled crossover design clinical trial conducted at the Mary MacKillop Institute for Health Research (MMIHR, Australia…

Australia20 participantsStarted 2025-07-08

Treatment: Breakfast meal challenge with tonic drink, Breakfast meal challenge with placebo drink

All recent trials (91 shown)

CompletedNot Applicable

NCT06394947

Fluid Challenge in Intensive Care The FENICE II Study

Fluids are considered the primary treatment for critically ill patients admitted to the intensive care unit (ICU), aiming to replace losses and or to enhance ve…

Italy4,734 participantsStarted 2025-01-01

Treatment: Fluid administration (any type)

CompletedPhase 1/2

NCT01073787

Intravenous Fluid for Pediatric Migraine in the Emergency Department

The purpose of this study is to evaluate the effect of intravenous fluid (0.9% sodium chloride and water) alone on headache pain in children with migraine visit…

Canada46 participantsStarted 2010-07

Treatment: Normal saline

Fluid Challenge

Trial phase breakdown

Trial status

Actively recruiting — 11 trials

Fluid Challenge and Plasma Volume, During Surgery

Reliability of Minimally Trained Operator's Velocity-Time Integral Measurement Guided by Artificial Intelligence VTI

Gluten Challenge in Celiac Disease - Which Formulation of Gluten Gives the Best Response?

Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness

Peripheral Tissue Perfusion in Intensive Care

Effect of a Liquid Tonic Drink on Post-meal Glucose and Insulin Responses

All recent trials (91 shown)

Fluid Challenge in Intensive Care The FENICE II Study

Intravenous Fluid for Pediatric Migraine in the Emergency Department

Trial phase breakdown

Trial status

Actively recruiting — 11 trials

Fluid Challenge and Plasma Volume, During Surgery

Reliability of Minimally Trained Operator's Velocity-Time Integral Measurement Guided by Artificial Intelligence VTI

Gluten Challenge in Celiac Disease - Which Formulation of Gluten Gives the Best Response?

Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness

Peripheral Tissue Perfusion in Intensive Care

Effect of a Liquid Tonic Drink on Post-meal Glucose and Insulin Responses

All recent trials (91 shown)

Fluid Challenge in Intensive Care The FENICE II Study

Intravenous Fluid for Pediatric Migraine in the Emergency Department

Role of End-Tidal CO2 During Passive Leg Raising to Predict Fluid Responsiveness in ICU

Fluid Responsiveness in Post-cardiac Surgery

Predictive Mini-bolus Fluid Responsiveness in Pediatric Septic Shock

Does the Time Between the End of Vascular Filling and Evaluation of Its Effectiveness Modify Fluid Challenge Results in…

Guided Fluid-balance Optimization With Mini-fluid chALlenge During Septic Shock

Hepatic Blood Flow Changes During Fluid Challenge Assessed by MRI in Volunteers Subjects.

Does the Response to a Mini-fluid Challenge of 3ml/kg in 2 Minutes Predict Fluid Responsiveness for Pediatric Patient?

Changes in Portal Vein Pulsatility Variability During a Tidal Volume Challenge Can Predict Fluid Tolerance

Comparison of 250 ml Versus 500 ml of Fluid Challenge

"Mini Fluid Challenge Assessment: a Comparison Among Three Hemodynamic Tools"

Study of Cardiac Power Index During Supine, Lateral, and Between Left and Right Positions During Two- and One-Lung Venti…

Effect of Oral Water in Healthy Volunteers on Cardiac Output, Regional Flow and Microcirculation in Healthy Volunteers

Changes in Pulse-Oximetry Perfusion Index Induced by Tidal Volume Challenge Versus Fluid Volume Challenge to Detect Prel…

Tidal Volume Challenge to Assess Volume Responsiveness

Hemodynamic Response to the End-expiratory Occlusion Test to Titrate Fluid Challenge in Operating Room.

Interest of the Pleth Variability Index in Neurosurgery

Fluid Challenge Impact in the Portal Vein Pulsatility Depending on the Fluid Responsivness Status

Haemodynamic and Respiratory Effects of a Low Positive End Expiratory Pressure Associated With a Fluid Challenge in Knee…