CompletedNot Applicable

Tidal Volume Challenge to Assess Volume Responsiveness

Greece50 participantsStarted 2022-03-30

Plain-language summary

The purpose of this study is to investigate the ability of changes in PPV and SVV after Tidal Volume Challenge to predict fluid responsiveness in patients undergoing general anesthesia with protective mechanical ventilation.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients over 18 years of age * General surgery or Vascular surgery patients without clamping of the aorta. * Will require arterial cannulation and invasive blood pressure monitoring during surgery * The expected duration of the operation will be equal to or greater than 90 minutes Exclusion Criteria: * preoperative arrhythmia or newly emergent arrhythmia after anesthesia induction * Reduced left (EF \< 40%) or right systolic function * BMI \>30 * Preoperative use of beta-blockers * Chronic obstructive pulmonary disease with FEV1 \<60% predicted volume

What they're measuring

Delta(Δ) PPV(T2-T1)

Timeframe: intraoperative, one hour and 3 minutes after anesthesia induction

Delta (Δ)SVV(T2-T1)

Timeframe: intraoperative, one hour and 3 minutes after anesthesia induction

Trial details

NCT IDNCT05254951

SponsorAttikon Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-19

View on ClinicalTrials.gov More Fluid Overload trials