Active — Not RecruitingNot Applicable

Study of Cardiac Power Index During Supine, Lateral, and Between Left and Right Positions During Two- and One-Lung Ventilation (OLV): Comparison of Hemodynamic Changes After Lung Recruitment Maneuver and Fluid Challenge Among Responders and Non-Responders (SVI, MAP, CPI Changes).

Greece60 participantsStarted 2025-05-06

Plain-language summary

The aim of this trial is to study the changes of the Cardiac Power Index (CPI) during supine and lateral decubitus position in two and one lung ventilation respectively. Moreover, CPI variations will be compared among patients in left versus patients in right lateral decubitus position. A secondary goal is to compare the changes in hemodynamic parameters after a lung recruitment maneuver during one lung ventilation and a fluid challenge test among patients that respond (responders) or do not respond to fluids (non-responders) according to changes of Stroke Volume Index (SVI) and Mean Arterial Pressure (MAP).

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age over 18 * Physical status ASA I-III (per the American Society of Anesthesiologists) * Fluent in Greek or English * Scheduled for thoracic surgery using a double-lumen endotracheal tube Exclusion Criteria: * Known arrhythmia * Severe valvular disease * Severe right or left ventricular dysfunction * Morbid obesity (BMI ≥ 40 kg/m²) * Inability to perform spirometry and/or echocardiography * Patient refusal to participate

What they're measuring

Change in Cardiac Power Index (CPI) Across Body Positions

Timeframe: up to 100 weeks

Trial details

NCT IDNCT07037225

SponsorMaria Fountoulaki

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05-06

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