FESS Operation

Clinical trial pipeline · Data from ClinicalTrials.gov

See which FESS Operation trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

RecruitingNot Applicable

NCT07368361

Th Study Wants to Compare the Best Technique for Sinus Operation in CRSWNP

This randomized controlled trial aims to compare the efficacy and safety of reboot surgery versus conventional full house FESS in patients with refractory CRSwN…

Canada40 participantsStarted 2026-01-01

Treatment: endoscopic nasal operation, Reboot operation" Complete removal of inflamed mucosa to periosteum"

RecruitingNot Applicable

NCT07286903

Fluorescence Enhanced Stereotactic Surgery (FESS)

Histopathological diagnosis is essential for gliomas, but stereotactic biopsy carries significant risks and can fail to provide diagnostic tissue. This study ai…

Italy20 participantsStarted 2024-07-01

RecruitingNot Applicable

NCT07181564

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodyna…

Greece150 participantsStarted 2025-09-11

Treatment: Propofol / Remifentanil, Ketamine + Magnesium sulfate (drug combination)

RecruitingNot Applicable

NCT06981494

Dexmedetomidine Versus Dexmedetomidine and Ketamine (Ketodex) in Ear and Nose Surgeries

The study aims to compare the efficacy, safety and overall effectiveness of dexmedetomidine and dexmedtomidine and ketamine (ketodex) in achieving controlled hy…

Egypt84 participantsStarted 2025-02-05

Treatment: Dexmedetomidine, Dexmedetomidine and ketamine ( Ketodex )

RecruitingPhase 2

NCT05882903

The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients with Chronic Rhinosinusitis…

To assess the safety and efficacy of one (single) application of Betamethasone Dipropionate Nasal Cream (BMDP CREAM) onto the sinus mucosa.

Australia24 participantsStarted 2023-08-17

Treatment: Betamethasone Dipropionate Nasal Cream 0.0644%, Pre-filled syringe and applicator device

All recent trials (51 shown)

CompletedNot Applicable

NCT07568873

Melatonin vs Metoprolol or Dexmedetomidine to Improve Surgical Field in FESS

This randomized controlled study at Zagazig University Hospitals will include 112 patients undergoing elective functional endoscopic sinus surgery, allocated in…

Egypt28 participantsStarted 2024-01-25

Treatment: Melatonin, Metoprolol (MET)

Active — Not RecruitingNot Applicable

NCT07548866

Comparison of Laryngeal Mask and Tracheal Intubation With and Without Topical Lidocaine Application

The study aims to identify the advantages and disadvantages of each of the three methods of airway management during FESS.

Russia150 participantsStarted 2026-04-01

Treatment: anesthesia of the respiratory tract with lidocaine, tracheal intubation

FESS Operation

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Th Study Wants to Compare the Best Technique for Sinus Operation in CRSWNP

Fluorescence Enhanced Stereotactic Surgery (FESS)

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

Dexmedetomidine Versus Dexmedetomidine and Ketamine (Ketodex) in Ear and Nose Surgeries

The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients with Chronic Rhinosinusitis…

All recent trials (51 shown)

Melatonin vs Metoprolol or Dexmedetomidine to Improve Surgical Field in FESS

Comparison of Laryngeal Mask and Tracheal Intubation With and Without Topical Lidocaine Application

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Th Study Wants to Compare the Best Technique for Sinus Operation in CRSWNP

Fluorescence Enhanced Stereotactic Surgery (FESS)

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

Dexmedetomidine Versus Dexmedetomidine and Ketamine (Ketodex) in Ear and Nose Surgeries

The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients with Chronic Rhinosinusitis…

All recent trials (51 shown)

Melatonin vs Metoprolol or Dexmedetomidine to Improve Surgical Field in FESS

Comparison of Laryngeal Mask and Tracheal Intubation With and Without Topical Lidocaine Application

Safety and Effectiveness of TurbAlign™ for Middle Turbinate Medialization After Functional Endoscopic Sinus Surgery

Optimal Dosage of Melatonin for Preoperative Sedation in FESS

Intratracheal Dexmedetomidine Versus Lidocaine for Smooth Tracheal Extubation

Best Practice in the Management of Concha Bullosa in FESS Operation

Functional Endoscopic Sinus Surgery Study

Nasal Dexmedetomidine Versus Systemic Infusion Dexmedetomidine in Reducing Intraoperative Opioid Consumption in Nasal En…

Auricular Neuromodulation for FESS

Comparative Study Between the Effect of Dexmedetomidine ,Midazolam or Bupivacaine Packing During FESS on Surgical Field…

The Effects of Objective Estimation of Pain Response

Mepolizumab to CRSwNP Through 12 Months - Randomised to FESS and Non-FESS Within the First 2 Weeks

Variants of Paranasal Sinuses in Nepali Population

Endoscopic Direct "Draf IIa" (Carolyn's Window Approach) Versus Endoscopic Angled "Draf IIa"Approach in Chronic Rhinosin…

Clinical Evaluation to Confirm Safety and Efficacy of Sinuplasty in the Paranasal Sinuses (CLEAR)

Canadian Health Economics, Outcome, and Effectiveness Comparison of Treatment in Patients With Chronic Rhinosinusitis

Intranasal Versus Intravenous Dexmedetomidine for Hypotensive Anesthesia in FESS

GLS-1200 Topical Nasal Spray to Prevent Sinusitis After Endoscopic Sinus Surgery

Dexmedetomidine Different Doses as Adjuvant to Entropy-assisted General Anesthesia During Functional Endoscopy Sinus Sur…

Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery