Active — Not RecruitingPhase 1/2

Functional Endoscopic Sinus Surgery Study

United States80 participantsStarted 2019-09-25

Plain-language summary

The aim of this study is to evaluate the effect of the addition of epinephrine to bilateral real time ultrasound guided pterygopalatine ganglion blocks on intra-operative bleeding and blood loss during functional endoscopic sinus surgery (FESS).

Who can participate

Age range18 Years – 90 Years

SexALL

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Inclusion criteria

✓. Patient presenting for bilateral FESS
✓. Adult patients (\>18 and \< 90 years old)
✓. Patient consents to participate
✓. No underlying chronic pain condition
✓. No underlying bleeding diathesis

Exclusion criteria

✕. Patient refuses to consent
✕. Patient requires revision or unilateral surgery
✕. Patient requires surgery in addition to FESS
✕. Age younger than 18 or older than 90 years
✕. Any underlying chronic pain condition
✕. History of bleeding diathesis
✕. Presence of any other factor which, at the discretion of any member of the study team, makes the patient a poor candidate for block placement.
✕. Presence of any other factor which, at the discretion of any member of the study team, makes the patient a poor candidate for research participation.

What they're measuring

Change in Endoscopic Grading of Nasal Bleeding

Timeframe: Every 10 minutes up to 36 hours

Trial details

NCT IDNCT03970655

SponsorUniversity of Florida

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01-23

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