Electronic Nicotine Delivery Systems

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Electronic Nicotine Delivery Systems trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

RecruitingNot Applicable

NCT06395415

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Electronic Nicotine Delivery Systems (ENDS) use remains prevalent among young adults, and many have high interest in quitting, yet research on effective interve…

United States46 participantsStarted 2025-04-25

Treatment: EQUIP, Standard Care

RecruitingNot Applicable

NCT05447325

Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Escalation in Young Adult ENDS Users

180 young adult vapers who are not current smokers will participate in a baseline functional magnetic resonance imaging (fMRI) experiment, prospectively linked…

United States180 participantsStarted 2022-07-15

Treatment: Exposure to Anti-Vaping Messages (generic themes then flavor-specific themes), Exposure to Anti-Vaping Messages (flavor-specific themes then generic themes)

All recent trials (73 shown)

Not Yet RecruitingNot Applicable

NCT07553585

Novel Labels to Improve Public Understanding of the Nicotine in Electronic Nicotine Delivery Systems: A Survey of Nicoti…

Current labels for the nicotine in e-cigarette/vaping products do not sufficiently convey information to the public. The aims of this study include developing a…

United States2,500 participantsStarted 2026-06

Treatment: Updated Labeling

CompletedNot Applicable

NCT05023096

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers

This study aims to better understand how the availability of electronic nicotine delivery system (aka electronic cigarettes) flavors (e.g., menthol, tobacco) im…

United States71 participantsStarted 2022-04-14

Treatment: Tobacco product administration and assessment

Electronic Nicotine Delivery Systems

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Escalation in Young Adult ENDS Users

All recent trials (73 shown)

Novel Labels to Improve Public Understanding of the Nicotine in Electronic Nicotine Delivery Systems: A Survey of Nicoti…

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Escalation in Young Adult ENDS Users

All recent trials (73 shown)

Novel Labels to Improve Public Understanding of the Nicotine in Electronic Nicotine Delivery Systems: A Survey of Nicoti…

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers

Smoking Cessation in Women With Gynecological Conditions

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers

Abuse Liability for Eight Electronic Nicotine Products

A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery Systems

E-cigarettes for Harm Reduction in Adults With Asthma

Trial on the Effect of E-cigarette Advertising on Cigarette Perceptions in Adolescents

Dual Use of ENDS and Combustible Cigarettes

Changes in Oral Health in Tobacco Cigarettes Smokers After Switching to Combustion-Free Nicotine Delivery Systems

Are Smokers Switching to Vaping at Lower Risk for Cancer? (Electronic Cigarettes and Cancer Risk)

The ESTxENDS Trial- Electronic Nicotine Delivery Systems as an Aid for Smoking Cessation-extension of Follow-up

CSD201203: A Study to Determine Subject Puffing Patterns of a Non-cylindrical, Closed, Electronic Nicotine Delivery Syst…

Influencer E-Cigarette and Cannabis Marketing: a Survey-Based Experiment Among Adolescents

Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems

Preference-based Tools for Smoking Cessation Among Disadvantaged Smokers, a Pragmatic Randomised Controlled Trial

Trial for Harm Reduction With Incentives & Vaping E-cigarettes

Effects of Dress by Adolescents on Electronic Cigarette Retailer Behaviors in China

Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes