Drug Addiction

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Drug Addiction trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 26 trials

RecruitingNot Applicable

NCT03745339

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Background: People with addictions often find it hard to choose the long-term benefits of abstinence over the short-term effects of using drugs. Researchers th…

United States150 participantsStarted 2019-06-07

RecruitingNot Applicable

NCT07340554

Neuroimaging of Adolescent Cannabis Use Treatment

This study is testing whether brain activity related to learning can help predict how well teens respond to a treatment program designed to reduce cannabis use.…

United States80 participantsStarted 2026-06

Treatment: Contingency Management, Elastic Net Regression

RecruitingNot Applicable

NCT07028983

Fighting Addictions, Improving Lives: COmprehensive Drug Rehabilitation With Music

FALCO is a parallel pragmatic randomized control trial addressing long-term effects of music therapy (MT) on substance use disorder (SUD). 600 participants wil…

Austria, Israel +2 more600 participantsStarted 2025-07-01

Treatment: Active Music Group (AMG), Music Listening Group (MLG)

RecruitingPhase 2

NCT04939623

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

The proposed clinical trial will address the problem of opioid withdrawal. Opioids are essential for pain-relief in the short term, but their continued use is a…

Canada40 participantsStarted 2023-10-31

Treatment: Probenecid

RecruitingNot Applicable

NCT05973838

Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention

The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for…

United States160 participantsStarted 2023-06-15

Treatment: Peer-Delivered Behavioral Activation ("Peer Activate")

RecruitingNot Applicable

NCT06880705

The Trans-Led Care Study

This study is testing a new mutual-help group called "the TLC program" for transgender adults who use substances or are recently in recovery. The TLC Program is…

United States124 participantsStarted 2025-02-10

Treatment: The TLC Program

All recent trials (100 shown)

CompletedPhase 1/2

NCT05976646

Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion

The overall goal of this project is to collect initial human data on the effects of novel compounds on safety (interactions with an opioid drug, e.g., buprenorp…

United States18 participantsStarted 2023-09-18

Treatment: Placebo, Auvelity

Not Yet RecruitingNot Applicable

NCT07414459

Combining Social Network Strategies and Routine Substance Use Screening

This study aims to improve health care for people who may have HIV or substance use disorders by bringing two services to a large community health center in Chi…

United States500 participantsStarted 2026-07-31

Treatment: Substance use disorder screening, Social network intervention

Drug Addiction

Trial phase breakdown

Trial status

Actively recruiting — 26 trials

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Neuroimaging of Adolescent Cannabis Use Treatment

Fighting Addictions, Improving Lives: COmprehensive Drug Rehabilitation With Music

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention

The Trans-Led Care Study

All recent trials (100 shown)

Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion

Combining Social Network Strategies and Routine Substance Use Screening

Trial phase breakdown

Trial status

Actively recruiting — 26 trials

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Neuroimaging of Adolescent Cannabis Use Treatment

Fighting Addictions, Improving Lives: COmprehensive Drug Rehabilitation With Music

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention

The Trans-Led Care Study

All recent trials (100 shown)

Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion

Combining Social Network Strategies and Routine Substance Use Screening

CB1R in Synthetic Psychoactive Cannabinoids

Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN)

Integrating Support Persons Into Recovery

Adapted RPM-08 for Substance Use Disorder in Pakistan

Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study

Effects of Circuit Training on Cardiopulmonary Fitness in Multi Drug Abusers

Effect of Semaglutide on Cannabis Use in Adults With Cannabis Use Disorder

Supporting Treatment Access and Recovery Through Linkage and Support

MEDiterranean Diet-driven Detoxification of OPioid Addicted patiEnts (MED-DOPE)

Evaluation of the ADD'Pro Vocational Reintegration Program (ADD-PRO-EVAL)

Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder

Semaglutide for Treatment of People With Methamphetamine Use Disorder: the SHIFT Study

PASCAL Feasibility Study

Mindfulness-Based Relapse Prevention to Improve Medication Assisted Treatment Adherence and Drug-use Outcomes for Opioid…

Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Opioid Use Disorders ("EXPO" Pilot Trial)

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study

Prescribe to Prevent HIV: A Hybrid Trial Helping Addiction Clinics Prevent HIV & Infections Through Safer Drug Use Suppo…