Cocaine Use Disorder (CUD)

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Cocaine Use Disorder (CUD) trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

RecruitingNot Applicable

NCT07071779

Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder

Substance misuse is one of the most common risk factors for health problems and premature death among adolescents and young adults worldwide. Although there are…

Switzerland210 participantsStarted 2025-07-23

Treatment: Substance-specific inhibition training, Control training

RecruitingEarly Phase 1

NCT05008146

Imaging CRF X NOP Interactions in CUD

This study uses \[11C\]NOP-1A positron emission tomography (PET) and a hydrocortisone challenge to image the interaction between nociceptive opioid peptide (NOP…

United States80 participantsStarted 2020-12-31

Treatment: Baseline [C-11]NOP-1A PET Scan, Hydrocortisone

All recent trials (11 shown)

CompletedPhase 1

NCT06273540

Phase1, STP7 Cocaine Drug-Drug Interaction Study

This is a double-blind, placebo-controlled, parallel group study to compare the effects of STP7 (mavoglurant) vs placebo control on i.v. cocaine's physiological…

United States21 participantsStarted 2024-04-15

Treatment: STP7 (mavoglurant), Placebo

Not Yet RecruitingNot Applicable

NCT07532460

The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine Users

The study aims to address the neurobiological basis of cognitive impairments in chronic cocaine users by investigating the potential impact of an acute potassiu…

Switzerland40 participantsStarted 2026-04

Treatment: 4-aminopyridine (4-AP), Placebo

Cocaine Use Disorder (CUD)

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder

Imaging CRF X NOP Interactions in CUD

All recent trials (11 shown)

Phase1, STP7 Cocaine Drug-Drug Interaction Study

The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine Users

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder

Imaging CRF X NOP Interactions in CUD

All recent trials (11 shown)

Phase1, STP7 Cocaine Drug-Drug Interaction Study

The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine Users

Temporal Window and Episodic Future Thinking in CUD

Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)

Multiple Ascending Dose Study of TMP-301 in Healthy Subjects

A Study to Investigate the Interaction Between TMP-301 and Cocaine.

Effect of rTMS on Neurotrophines Levels in CUD

Study to Investigate Whether AFQ056 Reduces Cocaine Use in Patients Diagnosed With Cocaine Use Disorder (CUD)

Subjective Sleep Quality in CUD TMS-Treated