Chronic Mental Disorders

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Chronic Mental Disorders trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 40 trials

RecruitingPhase 2

NCT06782724

Psilocybin Therapy for Psychological Distress in Palliative Patients

The goal of this clinical trial is to evaluate whether psilocybin therapy can effectively treat depression and psychological distress in adult patients with COP…

Czechia, Denmark +2 more108 participantsStarted 2025-07-01

Treatment: Psilocybin therapy

RecruitingNot Applicable

NCT07216261

Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0

Implementing Cognitive Behavioral Therapy for Insomnia with Older Veterans (SWELL): Function QUERI 3.0 aims to compare implementation approaches while also gath…

United States20 participantsStarted 2026-04-30

Treatment: Implementation Strategy: Foundational Arm, Implementation Strategy: REACH arm

RecruitingNot Applicable

NCT05914649

NC Testing in LC & POTS

Patients with Postural Orthostatic Tachycardia Syndrome (POTS) and Post-Acute Sequelae of COVID (PASC, or "Long COVID") experience cognitive dysfunction. The in…

Canada100 participantsStarted 2024-09-19

Treatment: IV normal saline (999 mL infusion), IV normal saline (50 mL infusion)

RecruitingNot Applicable

NCT06933173

RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis

We are studying the effect of a mind-body treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with or without Long COVID (LC).…

Canada200 participantsStarted 2025-07-10

Treatment: Dynamic neural retraining system

RecruitingNot Applicable

NCT06223503

VA Transitional Pain Service Study

The VA Community Care Program has provided an important resource to improve access to surgical care for Veterans unable to have treatment at VA Medical Centers…

United States400 participantsStarted 2024-03-01

Treatment: Transitional Pain Service

RecruitingPhase 1/2

NCT05548452

Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease

The purpose of this research study is to test the safety, tolerability, and effectiveness of the capsules that contain bacteria from healthy individuals when us…

United States80 participantsStarted 2022-11-21

Treatment: Intestinal Microbiota Transplant (IMT) Capsules, Placebo Capsules

All recent trials (100 shown)

TerminatedPhase 4

NCT05118204

Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization

Investigators will test a novel protocol for starting BUP (buprenorphine-naloxone) treatment. The BUP microdose induction protocol has participants start very l…

United States23 participantsStarted 2022-09-29

Treatment: BUP microdose induction, TAU

CompletedNot Applicable

NCT05786482

Evidence Based Mental Wellness Programming Online for Adults Across Chronic Physical Conditions

Chronic physical conditions are deﬁned as conditions that require ongoing management and treatment over extended periods of time. Chronic physical conditions ar…

Canada825 participantsStarted 2023-02-12

Treatment: Online mind-body wellness program, Online mind-body wellness program + Weekly Check-ins

Chronic Mental Disorders

Trial phase breakdown

Trial status

Actively recruiting — 40 trials

Psilocybin Therapy for Psychological Distress in Palliative Patients

Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0

NC Testing in LC & POTS

RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis

VA Transitional Pain Service Study

Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease

All recent trials (100 shown)

Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization

Evidence Based Mental Wellness Programming Online for Adults Across Chronic Physical Conditions

Trial phase breakdown

Trial status

Actively recruiting — 40 trials

Psilocybin Therapy for Psychological Distress in Palliative Patients

Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0

NC Testing in LC & POTS

RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis

VA Transitional Pain Service Study

Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease

All recent trials (100 shown)

Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization

Evidence Based Mental Wellness Programming Online for Adults Across Chronic Physical Conditions

Buprenorphine Treatment: A Safe Alternative for Opioid Dependent Pain Patients

Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled…

Improving Minority Health Through Biofeedback and Stress Reduction

Reflexology vs Progressive Muscle Relaxation for Fatigue in Hemodialysis Patients

A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia

Feasibility Testing a Meditation App for Professionals Working With Youth in the Legal System

Program Intensive Habilitation (PIH) for Young Children With Early Brain Damage

Problem-Solving Therapy for Patients With Chronic Disease and Poor Mental Well-being in General Practice

Closed-loop tDCS in Patients in Minimally Conscious State

Methylprednisolone in Patients With Cognitive Deficits in Post-COVID-19 Syndrome (PCS)

ADX-629 Therapy for Sjogren-Larsson Syndrome

The Effect of Physiotherapy Integrated With Yoga and Mindfulness on Individuals With Fibromyalgia

Ketogenic Diet to Reduce Osteoarthritis Pain in MCI

Identifying Therapeutic Hemodialysis Targets Through Cerebrovascular Reactivity; RESPIRACT 2

Computer Based Treatment for Cognitive Behavioral Therapy and Cooperative Pain Education and Self-Management

A Study of Medical Cannabis Aerosol Via the Fixed-dose Syqe Inhaler as an Add-on Treatment of Diabetic Peripheral Neurop…

Transcutaneous Auricular Vagal Nerve Stimulation for Post-coma Patients With Disorders of Consciousness

Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Comorbid Somatic Disease and Insomnia